Brief Article
Copyright ©2012 Baishideng. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2012; 4(9): 421-428
Published online Sep 16, 2012. doi: 10.4253/wjge.v4.i9.421
Efficacy of computed image modification of capsule endoscopy in patients with obscure gastrointestinal bleeding
Tomoaki Matsumura, Makoto Arai, Toru Sato, Tomoo Nakagawa, Daisuke Maruoka, Masaru Tsuboi, Sachio Hata, Eiji Arai, Tatsuro Katsuno, Fumio Imazeki, Osamu Yokosuka
Tomoaki Matsumura, Makoto Arai, Toru Sato, Tomoo Nakagawa, Daisuke Maruoka, Masaru Tsuboi, Sachio Hata, Eiji Arai, Tatsuro Katsuno, Fumio Imazeki, Osamu Yokosuka, Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba 2608670, Japan
Author contributions: Matsumura T and Arai M planned and conducted this project, analyzed the data and wrote this paper; Sato T, Nakagawa T, Maruoka D, Tsuboi M, Hata S, Arai E, Katsuno T, Imazeki F and Yokosuka O helped to plan the project.
Correspondence to: Makoto Arai, MD, Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chiba 2608670, Japan. araim-cib@umin.ac.jp
Telephone: +81-43-2262083 Fax: +81-43-2262088
Received: January 20, 2012
Revised: August 1, 2012
Accepted: September 12, 2012
Published online: September 16, 2012
Abstract

AIM: To investigate whether flexible spectral color enhancement (FICE) improves diagnostic yields of capsule endoscopy (CE) for obscure gastro-intestinal bleeding (OGIB).

METHODS: The study subjects consisted of 81 patients. Using FICE, there were three different sets with different wavelengths. Using randomly selected sets of FICE, images of CE were evaluated again by two individuals who were not shown the conventional CE reports and findings. The difference between FICE and conventional imaging was examined.

RESULTS: The overall diagnostic yields in FICE sets 1, 2, 3 and conventional imaging (48.1%) were 51.9%, 40.7%, 51.9% and 48.1%, respectively, which showed no statistical difference compared to conventional imaging. The total numbers of detected lesions per examination in FICE imaging and conventional imaging were 2.5 ± 2.1 and 1.8 ± 1.7, respectively, which showed a significant difference (P = 0.01).

CONCLUSION: The diagnostic yield for OGIB is not improved by FICE. However, FICE can detect significantly more small bowel lesions compared to conventional imaging.

Keywords: Computed virtual chromoendoscopy; Flexible spectral color enhancement; Capsule endoscopy; Obscure gastro-intestinal bleeding; Diagnostic yield