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World J Gastrointest Endosc. Aug 16, 2025; 17(8): 106087
Published online Aug 16, 2025. doi: 10.4253/wjge.v17.i8.106087
Advances in multibending endoscope: A paradigm shift in minimally invasive diagnostics and therapeutics
Xiang Song, Tao Mao, Xiao-Kai Chen, Lin-Lin Ren
Xiang Song, Tao Mao, Xiao-Kai Chen, Lin-Lin Ren, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Co-corresponding authors: Tao Mao and Lin-Lin Ren.
Author contributions: Song X and Chen XK performed literature search, edited and wrote original draft; Mao T and Ren LL reviewed the paper for important intellectual content, edited and finalized the text. Mao T and Ren LL contributed equally to this manuscript and are co-corresponding authors of this article.
Supported by the National Natural Science Foundation of China, No. 81602056 and No. 82273393; and the Young Talents Promotion Project of Shandong Medical Association in 2023, No. 2023_GJ_0087.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lin-Lin Ren, MD, Postdoc, Associate Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266000, Shandong Province, China. renlinlin@qdu.edu.cn
Received: February 24, 2025
Revised: April 7, 2025
Accepted: July 2, 2025
Published online: August 16, 2025
Processing time: 173 Days and 15.5 Hours
Abstract

Digestive endoscopy has been widely used in the diagnosis and treatment of digestive diseases. However, the anatomical complexity of specific lesions increases the difficulty of these operations, resulting in complications or treatment failure. Although various strategies, such as floss traction and the application of transparent caps, have been explored, their effectiveness remains limited due to individual differences in patients’ anatomical characteristics. The multibending (MB) endoscope represents a significant innovation as it is a conventional endoscope with an additional bending section and dual channels. Currently, this technology has been applied in gastroscopy, duodenoscopy and peroral cholangioscopy. The bending part of the endoscope facilitates its passage into difficult-to-reach anatomical regions and improves operating angles, thereby enhancing surgical precision and efficiency while reducing complication rates. Furthermore, the dual-channel design accelerates procedural workflows and increases operational versatility. This innovation is poised to transform endoscopic diagnosis and treatment of digestive system diseases. Since the MB endoscope is relatively new, further research is needed to comprehensively explore its benefits for and potential in endoscopic diagnosis and treatment. The aim of this review is to summarize the current research, indications, and future directions of MB endoscope.

Keywords: The multibending endoscope; Endoscopic submucosal dissection; Endoscopic mucosal resection; Peroral cholangioscopy; Endoscopic retrograde cholangiopancreatography; Complication

Core Tip: The multibending endoscope represents a transformative leap in the field of minimally invasive medical procedures. This technology, characterized by its enhanced flexibility and precision, allows for unprecedented access to complex anatomical structures. In addition, due to the realization of dual-channel operation, it is more efficient that operating with the multi-bending endoscope. This review elucidates the application of the multibending endoscope, underscoring its potential to revolutionize patient care.