Gravina AG, Pellegrino R, Romeo M, Palladino G, Cipullo M, Iadanza G, Olivieri S, Zagaria G, De Gennaro N, Santonastaso A, Romano M, Federico A. Quality of bowel preparation in patients with inflammatory bowel disease undergoing colonoscopy: What factors to consider? World J Gastrointest Endosc 2023; 15(3): 133-145 [PMID: 37034970 DOI: 10.4253/wjge.v15.i3.133]
Corresponding Author of This Article
Antonietta Gerarda Gravina, MD, PhD, Assistant Professor, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Miraglia, Naples 80138, Italy. antoniettagerarda.gravina@unicampania.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Mar 16, 2023; 15(3): 133-145 Published online Mar 16, 2023. doi: 10.4253/wjge.v15.i3.133
Quality of bowel preparation in patients with inflammatory bowel disease undergoing colonoscopy: What factors to consider?
Antonietta Gerarda Gravina, Raffaele Pellegrino, Mario Romeo, Giovanna Palladino, Marina Cipullo, Giorgia Iadanza, Simone Olivieri, Giuseppe Zagaria, Nicola De Gennaro, Antonio Santonastaso, Marco Romano, Alessandro Federico
Antonietta Gerarda Gravina, Raffaele Pellegrino, Mario Romeo, Giovanna Palladino, Marina Cipullo, Giorgia Iadanza, Simone Olivieri, Giuseppe Zagaria, Nicola De Gennaro, Antonio Santonastaso, Marco Romano, Alessandro Federico, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples 80138, Italy
Author contributions: Gravina AG, Pellegrino R, Romano M, and Federico A collected the literature and wrote the initial manuscript, conceptualized the table and figures, and contributed equally to this work; Gravina AG, Pellegrino R, Romeo M, Palladino G, Cipullo M, Iadanza G, Olivieri S, Zagaria G, De Gennaro N, Santonastaso A, Romano M, and Federico A conceptualized the structure of the text and critically revised the manuscript for important intellectual content; all authors read and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors declare no conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Antonietta Gerarda Gravina, MD, PhD, Assistant Professor, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Miraglia, Naples 80138, Italy. antoniettagerarda.gravina@unicampania.it
Received: November 11, 2022 Peer-review started: November 11, 2022 First decision: November 30, 2022 Revised: December 7, 2022 Accepted: February 15, 2023 Article in press: February 15, 2023 Published online: March 16, 2023 Processing time: 121 Days and 14.6 Hours
Abstract
An adequate bowel preparation in patients with inflammatory bowel disease (IBD) is a prerequisite for successful colonoscopy for screening, diagnosis, and surveillance. Several bowel preparation formulations are available, both high- and low-volume based on polyethylene glycol. Generally, low-volume formulations are also based on several compounds such as magnesium citrate preparations with sodium picosulphate, oral sulphate solution, and oral sodium phosphate-based solutions. Targeted studies on the quality of bowel preparation prior to colonoscopy in the IBD population are still required, with current evidence from existing studies being inconclusive. New frontiers are also moving towards the use of alternatives to anterograde ones, using preparations based on retrograde colonic lavage.
Core Tip: Obtaining adequate bowel preparation is challenging when treating a patient with inflammatory bowel disease (IBD) undergoing colonoscopy. Colonoscopy has multidimensional value ranging from diagnosis to disease surveillance and cancer screening. Although numerous data are available on bowel preparations in the general population, it is still unclear which preparation is the best for both efficacy and safety in patients with IBD. In addition, the factors that increase the risk of suboptimal preparation in IBD patients remain unclear.
