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Clinical Trials Study
Copyright ©The Author(s) 2026.
World J Hepatol. Jan 27, 2026; 18(1): 114366
Published online Jan 27, 2026. doi: 10.4254/wjh.v18.i1.114366
Table 1 Comparison of baseline characteristics between the intervention and control groups, n (%)/mean ± SD
Variable
Intervention group (n = 50)
Control group (n = 50)
Test statistic
P value
Sexχ2 = 1.1900.275
    Male40 (80.00)44 (88.00)
    Female10 (20.00)6 (12.00)
Age (years)51.62 ± 9.1754.98 ± 8.76t = -1.8640.065
Liver function grade (Child-Pugh score)Z = -0.1570.875
    Grade A11 (22.00)13 (26.00)
    Grade B29 (58.00)26 (52.00)
    Grade C10 (20.00)11 (22.00)
Marital statusχ2 = 0.3320.564
    Married42 (84.00)44 (88.00)
    Widowed/divorced8 (16.00)6 (12.00)
Medical payment methodZ = -0.9230.356
    Urban medical insurance8 (16.00)12 (24.00)
    Rural medical insurance36 (72.00)33 (66.00)
    Self-pay6 (12.00)5 (10.00)
    Duration of cirrhosis (years)8.32 ± 3.438.34 ± 3.37t = -0.0290.977
Presence of painχ2 = 0.3670.545
    Yes30 (60.00)27 (54.00)
    No20 (40.00)23 (46.00)
Presence of sleep problemsχ2 = 0.4070.523
    Yes35 (70.00)32 (64.00)
    No15 (30.00)18 (36.00)
Table 2 Comparison of psychological distress, anxiety, and depression scores between groups, median (interquartile range)/mean ± SD
GroupnPsychological distress score
Anxiety score
Depression score
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Intervention504 (4-5)3 (2-3)47.95 ± 5.3341.65 ± 4.2953.96 ± 4.8245.79 ± 3.25
Control504 (4-5)3 (3-4)48.54 ± 4.2346.38 ± 4.1853.32 ± 4.4750.14 ± 3.69
Z/tZ = -0.807Z = -5.771t = -0.618t = -5.583t = 0.677t = -6.25
P value0.4200.0000.5380.0000.5000.000
Table 3 Pre-intervention and post-intervention quality of life comparison between two patient groups, mean ± SD/median (interquartile range)
Group (n = 5)
Physiological domain
Psychological domain
Independence domain
Social relationships domain
Environment domain
Spiritual support/religion/personal belief
Overall quality of life score
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Experimental group11.27 ± 1.6514.40 ± 1.1712.16 ± 1.5214.57 ± 1.0911.77 ± 1.5914.08 ± 0.8912.56 ± 1.0513.15 ± 1.3612.98 ± 1.3713.34 ± 1.1312 (12-13)13 (12-14)10 (10-12)12 (12-13)
Control group11.49 ± 1.4312.37 ± 1.2012.41 ± 1.1913.05 ± 1.4511.71 ± 1.6112.11 ± 1.6412.11 ± 1.2912.25 ± 1.2913.03 ± 0.9713.13 ± 1.0512 (11-13)12 (11-13)10 (9-12)10 (10-12)
Z/tt = -0.711t = 8.559t = -0.912t = 5.908t = 0.191t = 7.495t = 0.968t = 3.397t = -0.249t = 0.990Z = -0.813Z = -2.744Z = -0.443Z = -6.330
P value0.47900.36400.84900.3370.0010.8040.3250.4160.0060.6580
Table 4 Comparison of satisfaction scores for care nursing between two groups of patients, mean ± SD
Group
Sample size
Pre-intervention
Post-intervention
Experimental group50112.90 ± 6.24144.28 ± 4.43
Control group50113.50 ± 7.26125.78 ± 8.39
t value-0.4414.23
P value0.660.001