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©The Author(s) 2025.
World J Hepatol. Mar 27, 2025; 17(3): 101721
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.101721
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.101721
Table 1 The top 10 productive countries related to artificial intelligence for liver disease
| Country | Counts | Ranking on the basis of total documents | Total citations | Ranking on the basis of total citations | Average citation | Ranking on the basis of total link strength | Link strength |
| China | 1568 | 1 | 21137 | 2 | 13.48 | 2 | 678 |
| United States | 1062 | 2 | 25084 | 1 | 23.62 | 1 | 1034 |
| Italy | 318 | 3 | 6629 | 3 | 20.85 | 3 | 605 |
| Germany | 277 | 4 | 6377 | 4 | 23.02 | 5 | 539 |
| Japan | 258 | 5 | 5716 | 5 | 22.16 | 7 | 374 |
| United Kingdom | 234 | 6 | 5312 | 6 | 22.70 | 4 | 559 |
| South Korea | 211 | 7 | 3935 | 8 | 18.65 | 9 | 339 |
| France | 175 | 8 | 4423 | 7 | 25.27 | 6 | 503 |
| India | 165 | 9 | 3245 | 9 | 19.67 | 18 | 167 |
| Canada | 118 | 10 | 3066 | 11 | 25.98 | 11 | 261 |
Table 2 The top ten institutions by volume of the application of artificial intelligence to liver disease
| Rank | Country | Counts | Institution | Citation | Mean citation |
| 1 | China | 104 | Chinese Academy of Sciences | 2088 | 20.08 |
| 2 | China | 96 | Fudan University | 1465 | 15.26 |
| 3 | China | 93 | Zhejiang University | 1366 | 14.69 |
| 4 | China | 92 | Sun Yat-Sen University | 1833 | 19.92 |
| 5 | China | 64 | Shanghai Jiao Tong University | 732 | 11.44 |
| 6 | China | 63 | Sichuan University | 606 | 9.62 |
| 7 | United States | 56 | University of Pittsburgh | 1815 | 32.41 |
| 8 | China | 53 | Capital Medical University | 735 | 13.87 |
| 9 | China | 52 | Stanford University | 1308 | 25.15 |
| 10 | China | 47 | Chinese People’s Liberation Army General Hospital | 858 | 18.26 |
Table 3 The top ten most productive authors on artificial intelligence in liver disease
| Rank | Author | Counts | Total citations | Mean citations |
| 1 | Sucandy Iswanto | 32 | 501 | 15.66 |
| 2 | Ross Sharona | 25 | 176 | 7.04 |
| 3 | Rosemurgy Alexander | 23 | 442 | 19.22 |
| 4 | Wang Wei | 19 | 23 | 1.21 |
| 5 | Tian Jie | 17 | 508 | 29.88 |
| 6 | Goh Brian K. P. | 17 | 177 | 10.41 |
| 7 | Liu Rong | 17 | 225 | 13.24 |
| 8 | Pawlik Timothy M. | 17 | 218 | 12.82 |
| 9 | Song Bin | 16 | 131 | 8.19 |
| 10 | Di Benedetto Fabrizio | 15 | 546 | 36.40 |
Table 4 The top 10 journals related to artificial intelligence in the field of liver disease
| Rank | Journal title | Countries | Count | Impact factor (2023) | JCR (2023) | Total citations |
| 1 | Frontiers in Oncology | Switzerland | 89 | 4.7 | Q2 | 655 |
| 2 | Scientific Reports | England | 82 | 4.6 | Q2 | 1000 |
| 3 | Asian Journal of Surgery | China | 77 | 3.5 | Q1 | 553 |
| 4 | European Radiology | Germany | 73 | 5.9 | Q1 | 1672 |
| 5 | Surgical Endoscopy and Other Interventional Techniques | United States | 73 | 3.1 | Q1 | 1763 |
| 6 | Cancers | Switzerland | 69 | 5.2 | Q2 | 317 |
| 7 | Plos One | United States | 67 | 3.7 | Q2 | 1321 |
| 8 | World Journal of Gastroenterology | China | 55 | 4.3 | Q2 | 950 |
| 9 | Diagnostics | Poland | 51 | - | - | 159 |
| 10 | Medical Physics | United States | 42 | 3.8 | Q2 | 717 |
Table 5 The top ten most cited articles related to artificial intelligence in the field of liver disease
| Title | Journals | First author | Year | Citations |
| Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries | CA Cancer J Clin | Freddie Bray | 2018 | 148 |
| Deep Learning with Convolutional Neural Network for Differentiation of Liver Masses at Dynamic Contrast-enhanced CT: A Preliminary Study | Radiology | Koichiro Yasaka | 2018 | 128 |
| EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma | J Hepatol | European Association for the Study of the Liver | 2018 | 117 |
| Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries | CA Cancer J Clin | Hyuna Sung | 2021 | 112 |
| Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases | Hepatology | Jorge A Marrero | 2018 | 109 |
| AASLD guidelines for the treatment of hepatocellular carcinoma | Hepatology | Julie K Heimbach | 2018 | 91 |
| Radiomics: Images Are More than Pictures, They Are Data | Radiology | Robert J Gillies | 2016 | 89 |
| Radiomic analysis of contrast-enhanced CT predicts microvascular invasion and outcome in hepatocellular carcinoma | J Hepatol | Xun Xu | 2019 | 88 |
| Deep learning Radiomics of shear wave elastography significantly improved diagnostic performance for assessing liver fibrosis in chronic hepatitis B: A prospective multicenter study | Gut | Kun Wang | 2019 | 85 |
| A survey on deep learning in medical image analysis | Med Image Anal | Geert Litjens | 2017 | 78 |
Table 6 The top 30 keywords with the highest frequency of application of artificial intelligence to liver disease
| Rank | Keywords | Count | Rank | Keywords | Count | Rank | Keywords | Count |
| 1 | Hepatocellular carcinoma | 1023 | 11 | Survival | 206 | 21 | CT | 145 |
| 2 | Machine learning | 551 | 12 | Model | 202 | 22 | System | 144 |
| 3 | Deep learning | 393 | 13 | Resection | 200 | 23 | Neural network | 139 |
| 4 | Cancer | 377 | 14 | Outcome | 195 | 24 | Experience | 133 |
| 5 | Diagnosis | 310 | 15 | Disease | 190 | 25 | Robotic surgery | 132 |
| 6 | Classification | 294 | 16 | Expression | 190 | 26 | Liver resection | 124 |
| 7 | Artificial intelligence | 291 | 17 | Liver | 175 | 27 | Identification | 122 |
| 8 | Surgery | 235 | 18 | Management | 169 | 28 | Computed tomography | 120 |
| 9 | Prediction | 219 | 19 | Convolutional neural network | 167 | 29 | Fatty liver disease | 120 |
| 10 | Risk | 210 | 20 | Cirrhosis | 163 | 30 | Cell | 116 |
- Citation: Zhou XQ, Huang S, Shi XM, Liu S, Zhang W, Shi L, Lv MH, Tang XW. Global trends in artificial intelligence applications in liver disease over seventeen years. World J Hepatol 2025; 17(3): 101721
- URL: https://www.wjgnet.com/1948-5182/full/v17/i3/101721.htm
- DOI: https://dx.doi.org/10.4254/wjh.v17.i3.101721
