Interleukin-36 subfamily cytokines in liver diseases

doi:10.4254/wjh.v17.i9.109429

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Sep 27, 2025 (publication date) through Sep 25, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Sep 27, 2025; 17(9): 109429
Published online Sep 27, 2025. doi: 10.4254/wjh.v17.i9.109429

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Figure 1 The role of interleukin-36 in liver disease. In the context of liver diseases, interleukin-36 cytokines may activate a variety of immune and nonimmune cells in the liver, including dendritic cells, macrophages, T cells, and fibroblasts. IL: Interleukin; NF-κB: Nuclear factor-κB; MAPK: Mitogen-activated protein kinase; CXCL1: C-X-C motif ligand 1; Th 17 cells: T helper type 17 cells; GM-CSF: Granulocyte-macrophage colony-stimulating factor; IL-36Ra: Interleukin-36 receptor antagonist.

Citation: Xiong ZK, Gu SM, Zheng YY. Interleukin-36 subfamily cytokines in liver diseases. World J Hepatol 2025; 17(9): 109429
URL: https://www.wjgnet.com/1948-5182/full/v17/i9/109429.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i9.109429