Potential role of noninvasive biomarkers during liver fibrosis

doi:10.4254/wjh.v13.i12.1919

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Dec 27, 2021 (publication date) through Nov 22, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Dec 27, 2021; 13(12): 1919-1935
Published online Dec 27, 2021. doi: 10.4254/wjh.v13.i12.1919

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Figure 1 Factors promoting liver cell injury leading to fibrosis, cirrhosis, and carcinoma. NAFLD: Non-alcoholic fatty liver disease; HBV: Hepatitis B virus; HCV: Hepatitis C virus; PDGF: Platelet growth factor; IGF: Insulin-like growth factor; TGF: Tissue growth factor; ROS: Reactive oxygen species; ET-1: Endothelin-1; EMT: Epithelial-mesenchymal transition.

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Figure 2 Various methods for assessment of liver fibrosis. MRI: Magnetic resonance imaging; TE: Transient elastography; SWE: Shear wave elastography; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; AAR: Aspartate aminotransferase aspartate aminotransferase/alanine aminotransferase ratio; TGF-β: Transforming growth factor β; PDGF: Platelet growth factor; APRI: Aspartate aminotransferase to platelet count ratio; FIB-4: Fibrosis-4; PCICP: Procollagen type 1; PCIIINP: Procollagen type 3; MMP: Matrix metalloproteinase.

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Figure 3 Process of microRNA biogenesis. miRNA: MicroRNA.

Citation: Kaur N, Goyal G, Garg R, Tapasvi C, Chawla S, Kaur R. Potential role of noninvasive biomarkers during liver fibrosis. World J Hepatol 2021; 13(12): 1919-1935
URL: https://www.wjgnet.com/1948-5182/full/v13/i12/1919.htm
DOI: https://dx.doi.org/10.4254/wjh.v13.i12.1919