Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease

Figure 1 Variability of histological specimens in HE (top) and PicroSirius red (bottom) stained transjugular biopsy specimens. A: Non-cirrhotic sample with 0.01% fibrosis proportion; B: Cirrhotic sample with 21% of fibrosis proportion.

Figure 2 Correlation between hepatic venous pressure gradient and fibrosis density measured by collagen proportionate area. A: Correlation between HVPG and fibrosis density measured by CPA in the whole group of patients; B: Subgroup analysis showing a positive correlation between CPA and HVPG restricted to active alcohol drinkers. HVPG: Hepatic venous pressure gradient; CPA: Collagen proportionate area.

Figure 3 Relationship between hepatic venous pressure gradient (A), collagen proportionate area (B) and development of clinical complications related to portal hypertension during follow-up both in active alcohol drinkers (C) and abstinent patients (D).