©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Hepatitis C virus infection and thyroid autoimmune disorders: A model of interactions between the host and the environment
Francesca Pastore, Antonio Martocchia, Manuela Stefanelli, Pietro Prunas, Stefania Giordano, Lavinia Toussan, Antonio Devito, Paolo Falaschi, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, 00189 Rome, Italy
Author contributions: All authors contributed to the manuscript.
Conflict-of-interest statement: No financial conflicts of interest or other relationships are present in the manuscript.
Correspondence to: Francesca Pastore, MD, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, Via di Grottarossa 1035/39, 00189 Rome, Italy. francesca.past@virgilio.it
Telephone: +39-6-33775467 Fax: +39-6-33775401
Received: April 28, 2015
Peer-review started: May 6, 2015
First decision: October 14, 2015
Revised: October 28, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 18, 2016
Processing time: 261 Days and 11.9 Hours
Peer-review started: May 6, 2015
First decision: October 14, 2015
Revised: October 28, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 18, 2016
Processing time: 261 Days and 11.9 Hours
Core Tip
Core tip: This review examines the relationship between the hepatitis C virus (HCV) infection and the thyroid autoimmunity, on the basis of recent evidence of the literature about the mechanisms of self tolerance and thyroid damage related to HCV. The advances in the HCV infection treatment have been discussed in the paper, with relevant clinical results.