©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 8, 2015; 7(7): 942-953
Published online May 8, 2015. doi: 10.4254/wjh.v7.i7.942
Published online May 8, 2015. doi: 10.4254/wjh.v7.i7.942
Incidence, risk factors and outcome of de novo tumors in liver transplant recipients focusing on alcoholic cirrhosis
Carlos Jiménez-Romero, Iago Justo-Alonso, Félix Cambra-Molero, Jorge Calvo-Pulido, Álvaro García-Sesma, Manuel Abradelo-Usera, Oscar Caso-Maestro, Alejandro Manrique-Municio, Service of General and Digestive Surgery, Abdominal Organ Transplantation, “Doce de Octubre”, University Hospital, Universidad Complutense de Madrid, 28041 Madrid, Spain
Author contributions: All authors equally contributed to this paper.
Conflict-of-interest: None to declare.
Correspondence to: Carlos Jiménez-Romero, MD, PhD, FACS, Service of General and Digestive Surgery, Abdominal Organ Transplantation, “Doce de Octubre”, University Hospital, Universidad Complutense de Madrid, Ctra de Andalucía km 5,4., 28041 Madrid, Spain. luiscarlos.jimenez@salud.madrid.org
Telephone: +34-91-3908077 Fax: +34-91-3908077
Received: July 21, 2014
Peer-review started: July 28, 2014
First decision: August 14, 2014
Revised: September 15, 2014
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: May 8, 2015
Processing time: 295 Days and 13.4 Hours
Peer-review started: July 28, 2014
First decision: August 14, 2014
Revised: September 15, 2014
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: May 8, 2015
Processing time: 295 Days and 13.4 Hours
Core Tip
Core tip: Incidence of de novo tumors is significantly increased in patients who undergo liver transplantation for alcoholic cirrhosis. The association of alcohol and tobacco consumption and immunosuppression contribute to the development of de novo malignancies, mainly located in upper aerodigestive tract, lung and skin.