Evidence-based consensus on the diagnosis, prevention and management of hepatitis C virus disease

doi:10.4254/wjh.v7.i3.616

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Mar 27, 2015; 7(3): 616-627
Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.616

Evidence-based consensus on the diagnosis, prevention and management of hepatitis C virus disease

Mahrukh Akbar Shaheen, Muhammad Idrees

Mahrukh Akbar Shaheen, Muhammad Idrees, Division of Molecular Virology, National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore 53700, Pakistan

Author contributions: Shaheen MA drafted the manuscript; Idrees M conceived, designed and critically revised the manuscript for important intellectual content.

Conflict-of-interest: The authors declare that they have no competing interests.

Correspondence to: Dr. Muhammad Idrees, Associate Professor, Head, Division of Molecular Virology, National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore 53700, Pakistan. idreeskhan@cemb.edu.pk

Telephone: +92-42-35293141 Fax: +92-42-35293141

Received: August 25, 2014
Peer-review started: August 26, 2014
First decision: September 19, 2014
Revised: October 1, 2014
Accepted: December 3, 2014
Article in press: December 3, 2014
Published online: March 27, 2015
Processing time: 217 Days and 21.7 Hours

Core Tip

Core tip: The present review describes the evidence-based consensus on the diagnosis, prevention and management of hepatitis C virus (HCV) disease. Besides the conventional techniques more advanced technologies have come to the front that provides best detection with greater ease and specificity. It is of immense importance to prevent this infection among the sexual partners, injecting drug users, mother-to-infant transmission of HCV, household contact, healthcare workers and people who get tattoos and piercing on their skin. Management includes examining the treatment, assessment of hepatic condition before commencing therapy, controlling the parameters upon which dual and triple therapies work, monitoring after treatment and adjusting the co-factors.