©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Oct 8, 2015; 7(22): 2389-2395
Published online Oct 8, 2015. doi: 10.4254/wjh.v7.i22.2389
Published online Oct 8, 2015. doi: 10.4254/wjh.v7.i22.2389
Hepatitis delta virus: Making the point from virus isolation up to 2014
Raffaella Romeo, Riccardo Perbellini, 1st Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, University of Milan, 20122 Milano, Italy
Author contributions: Romeo R performed the literature search, data analysis, writing of the paper, created the figures; Perbellini R contributed to data analysis and manuscript revision.
Conflict-of-interest statement: The authors declare no conflict of interest.
Correspondence to: Raffaella Romeo, MD, PhD, 1st Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, University of Milan, via F. Sforza, 35, 20122 Milan, Italy. raffaella.romeo@policlinico.mi.it
Telephone: +39-2-55035432 Fax: +39-2-50320379
Received: January 31, 2015
Peer-review started: February 2, 2015
First decision: May 13, 2015
Revised: September 6, 2015
Accepted: September 16, 2015
Article in press: September 18, 2015
Published online: October 8, 2015
Processing time: 244 Days and 7.5 Hours
Peer-review started: February 2, 2015
First decision: May 13, 2015
Revised: September 6, 2015
Accepted: September 16, 2015
Article in press: September 18, 2015
Published online: October 8, 2015
Processing time: 244 Days and 7.5 Hours
Core Tip
Core tip: The re-appearance of hepatitis delta virus infection in developed Countries has risen new interest on one of the most severe forms of viral hepatitis in humans. The lack of research on the subject for about two decades is responsible for the present unavailability of specific and efficient antiviral treatments against hepatitis delta virus. This review focuses on what is known up today and what still needs to be done.