Enomoto H, Sakai Y, Iwata Y, Takata R, Aizawa N, Ikeda N, Hasegawa K, Nakano C, Nishimura T, Yoh K, Ishii A, Takashima T, Nishikawa H, Iijima H, Nishiguchi S. Development of risky varices in alcoholic cirrhosis with a well-maintained nutritional status. World J Hepatol 2015; 7(21): 2358-2362 [PMID: 26413226 DOI: 10.4254/wjh.v7.i21.2358]
Corresponding Author of This Article
Hirayuki Enomoto, MD, PhD, Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo 663-8501, Japan. enomoto@hyo-med.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hirayuki Enomoto, Yoshiyuki Sakai, Yoshinori Iwata, Ryo Takata, Nobuhiro Aizawa, Naoto Ikeda, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Akio Ishii, Tomoyuki Takashima, Hiroki Nishikawa, Hiroko Iijima, Shuhei Nishiguchi, Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo 663-8501, Japan
Author contributions: All authors participated in the studies; Enomoto H and Sakai Y wrote and edited the manuscript; all authors were involved in the manuscript revision and approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by Hyogo College of Medicine ethics committee.
Informed consent statement: Written informed consent about personal and medical data collection was obtained from all patients.
Conflict-of-interest statement: None of the authors have conflicts of interest to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hirayuki Enomoto, MD, PhD, Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo 663-8501, Japan. enomoto@hyo-med.ac.jp
Telephone: +81-798-456472 Fax: +81-798-456474
Received: June 19, 2015 Peer-review started: June 20, 2015 First decision: July 27, 2015 Revised: August 5, 2015 Accepted: September 7, 2015 Article in press: September 8, 2015 Published online: September 28, 2015 Processing time: 95 Days and 15.8 Hours
Core Tip
Core tip: We compared the nutritional status between alcoholic compensated cirrhotic patients and hepatitis C virus (HCV)-related cirrhotic compensated patients. The levels of rapid-turnover proteins in alcoholic compensated cirrhotic patients were significantly higher than those in HCV-related compensated cirrhotic patients. When the nutritional status was determined using the albumin level and non-protein respiratory quotient, the frequency of having a normal nutritional status in alcoholic compensated cirrhotic patients was significantly higher than that in HCV-related compensated cirrhotic patients. These findings suggest that alcoholic compensated cirrhotic patients can develop severe portal hypertension even with a relatively well-maintained liver function and nutritional status.
