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Letter to the Editor: Filling the gaps in non-invasive assessment of liver fibrosis in metabolic dysfunction-associated steatotic liver disease
Roberta Forlano, Nicola Maurizio Castellaneta, Gastroenterology Unit, General Regional Hospital “F Miulli”, Acquaviva delle Fonti 70021, Puglia, Italy
Roberta Forlano, Patrizia Suppressa, Department of Medicine, LUM University, Casamassima 70010, Puglia, Italy
Patrizia Suppressa, Department of Internal Medicine, General Regional Hospital “F Miulli”, Acquaviva delle Fonti 70021, Puglia, Italy
Author contributions: Forlano R wrote the manuscript; Catellaneta NM and Suppreessa P reviewed the draft; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Corresponding author: Roberta Forlano, MD, PhD, Associate Professor, Gastroenterology Unit, General Regional Hospital “F Miulli”, Strada Provinciale Acquaviva-Santeramo, Acquaviva delle Fonti 70021, Puglia, Italy. forlano@lum.it
Received: December 16, 2025
Revised: January 14, 2026
Accepted: February 2, 2026
Published online: August 27, 2026
Processing time: 245 Days and 20.4 Hours
Revised: January 14, 2026
Accepted: February 2, 2026
Published online: August 27, 2026
Processing time: 245 Days and 20.4 Hours
Core Tip
Core Tip: Non-invasive assessment of liver fibrosis remains challenging in patients suffering from metabolic dysfunction associated steatotic liver disease. A two-tier system including blood tests and elastography still remains the most sensible and practical approach to address this unmet need.