Uncovering silent carriers: Hematological insights and viral burden in incidentally detected hepatitis B virus infection
Manisha M Ratnaparkhi, Chanda R Vyawahare, Parag J Ratnakar, Nageswari R Gandham, Poonam V Suryawanshi
Manisha M Ratnaparkhi, Chanda R Vyawahare, Nageswari R Gandham, Department of Microbiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pune 411018, Mahārāshtra, India
Parag J Ratnakar, Central Clinical Laboratory, Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pune 411018, Mahārāshtra, India
Poonam V Suryawanshi, Central Research Facility, Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pune 411018, Mahārāshtra, India
Author contributions: Ratnaparkhi MM was responsible for concept and design of the study, manuscript writing; Ratnaparkhi MM, Vyawahare CR, and Suryawanshi PV contributed to statistical analysis; Ratnaparkhi MM and Suryawanshi PV were contributed to methodology; Ratnaparkhi MM, Vyawahare CR, and Gandham NR contributed to literature search; Vyawahare CR edited the manuscript; Ratnakar PJ was involved with collection and testing of the clinical samples; Gandham NR was responsible for data interpretation; Ratnaparkhi MM, Vyawahare CR, Ratnakar PJ, Gandham NR, and Suryawanshi PV finalized manuscript. All authors have reviewed and approved the manuscript.
Institutional review board statement: The study was conducted following approval from the Institutional Ethics Committees. Approval references included IESC research from Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India (approval No. I.E.S.C/163/2023).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and/or analyzed during the current study are available from the corresponding author upon request
via email
chandavyawahare@dpu.edu.in.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Chanda R Vyawahare, MD, Professor, Department of Microbiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune 411018, Mahārāshtra, India.
chandavyawahare@dpu.edu.in
Received: August 20, 2025
Revised: September 11, 2025
Accepted: November 25, 2025
Published online: January 27, 2026
Processing time: 160 Days and 16 Hours
