Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jan 27, 2025; 17(1): 101664
Published online Jan 27, 2025. doi: 10.4254/wjh.v17.i1.101664
Hepatic eosinophilic pseudotumor due to Fasciola hepatica infection mimicking intrahepatic cholangiocarcinoma: A case report
Kim-Long Le, Minh-Quang Tran, Tri-Nhan Pham, Nhu Ngoc-Quynh Duong, Thien Thuan Dinh, Nguyen-Khoi Le
Kim-Long Le, Minh-Quang Tran, Tri-Nhan Pham, Nguyen-Khoi Le, Department of Surgery, Pham Ngoc Thach University of Medicine, Ho Chi Minh 07000, Viet Nam
Kim-Long Le, Thien Thuan Dinh, Nguyen-Khoi Le, Department of Hepato-Pancreato-Biliary, Nhan Dan Gia Dinh Hospital, Ho Chi Minh 07000, Viet Nam
Nhu Ngoc-Quynh Duong, Department of Surgery, District 4 Hospital, Ho Chi Minh 07000, Viet Nam
Author contributions: Le KL conceptualized the case report and supervised its generation; Pham TN was responsible for data visualization; Tran MQ, Dinh TT, and Duong NNQ contributed to investigation of the patient in the clinical setting and the literature search; Le KL and Tran MQ wrote the original draft of the manuscript; Le KL and Le NK reviewed and edited the successive versions of the manuscript. All authors reviewed and approved the final version of the manuscript.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nguyen-Khoi Le, PhD, Department of Surgery, Pham Ngoc Thach University of Medicine, 02 Duong Quang Trung Street, Ward 12, District 10, Ho Chi Minh 07000, Viet Nam. tg_lenguyenkhoi@pnt.edu.vn
Received: September 23, 2024
Revised: November 5, 2024
Accepted: November 19, 2024
Published online: January 27, 2025
Processing time: 105 Days and 18.7 Hours
Core Tip

Core Tip: This manuscript presents a case of hepatic eosinophilic pseudotumor (HEPT) misdiagnosed as intrahepatic cholangiocarcinoma, later confirmed to be caused by Fasciola hepatica infection. HEPT, a rare benign condition characterized by dense eosinophilic infiltration, mimics malignant hepatic tumors, posing significant diagnostic challenges. The report emphasizes the importance of histopathological and serological analyses in differentiating HEPT from malignancies, especially in endemic regions. The case demonstrated the efficacy of triclabendazole in resolving HEPT secondary to parasitic infection, highlighting the need for awareness of parasitic causes in atypical hepatic lesions.