Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 27, 2024; 16(8): 1120-1130
Published online Aug 27, 2024. doi: 10.4254/wjh.v16.i8.1120
Correlation between non-alcoholic fatty liver disease and metabolic parameters in persons with newly diagnosed type 2 diabetes mellitus
Anne Phillips, Chun Shing Kwok, Sushmita Mukherjee, Supriyo Mukherjee
Supriyo Mukherjee, Department of Medicine, Research Centre for Diabetes Hypertension and Obesity, Samastipur 848101, India
Sushmita Mukherjee, Department of Clinical Ultrasonography, Research Centre for Diabetes Hypertension and Obesity, Samastipur 848101, India
Chun Shing Kwok, Cardiology Registrar, University Hospitals of North Midlands NHS Trust United Kingdom, Staffordshire ST4 6QG, United Kingdom
Anne Phillips, Faculty of Health Education and Life Sciences, Department of Post-Qualifying Healthcare Practice, Birmingham City University, Birmingham B4 7AP, United Kingdom
Author contributions: Mukherjee S and Mukherjee S conceptualized the study and performed the data curation and analysis; Kwok CS and Phillips A contributed to the study methodology and interim manuscript review. All authors reviewed and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Gurushree Hi-Tech Multispecialty Hospital Ethics Committee (No. 8/22/004IEC) and the Faculty Academic Ethics Committee in the Health, Education and Life Sciences at Birmingham City University (Mukherjee/#10953/sub2/R(C)/2022/Nov/HELS FAEC).
Informed consent statement: As this study falls under the category of epidemiological research and involves the analysis of existing data without direct patient contact or intervention, the need for obtaining informed consent from individual participants was deemed unnecessary. Therefore, no informed consent form was utilized in this study.
Conflict-of-interest statement: The authors declare that they each have no conflicts of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Supriyo Mukherjee, MD, Doctor, Department of Medicine, Research Centre for Diabetes Hypertension and Obesity, Bengali Tola, Bihar, Samastipur 848101, India. supriyorcdho@outlook.com
Received: January 4, 2024
Revised: June 6, 2024
Accepted: July 17, 2024
Published online: August 27, 2024
Processing time: 230 Days and 10.3 Hours
Core Tip

Core Tip: This study evaluated the association between type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). Nearly 3 of 4 patients with T2DM had evidence of NAFLD. This study also concluded that NAFLD is common in patients who consume high amounts of fats and oils. A higher percentage of females were diagnosed with NAFLD and exhibited higher body mass index, waist circumference and lipid levels. Serum alanine aminotransferase levels have potential as a screening tool, aligning with recommendations for universal screening in T2DM populations. Early identification of NAFLD in T2DM patients may enable interventions to mitigate disease progression.