Published online Sep 27, 2022. doi: 10.4254/wjh.v14.i9.1704
Peer-review started: March 9, 2022
First decision: June 22, 2022
Revised: July 4, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: September 27, 2022
Processing time: 197 Days and 7.1 Hours
Core Tip: The overstitch endoscopic suturing system (Overstitch; Apollo Endosurgery, Austin, Tex) which was first reported in 2013, allows sleeve gastropexy to be performed by placing full-thickness sutures through the gastric wall from the pre-pyloric antrum to the gastro-oesophageal junction. Performed using flexible endoscopy, it has the advantage of being less invasive with no permanent visible scar and evidence suggestive of fewer complications compared to laparoscopic sleeve gastrectomy. There is now mounting evidence not only showing benefits in terms of weight loss but also improvements in other metabolic markers including Hemoglobin A1c, blood pressure and alanine aminotransferase, making endoscopic sleeve gastroplasty potentially a viable treatment option for non-alcoholic fatty liver disease in the future.