Keung CY, Morgan A, Le ST, Robertson M, Urquhart P, Swan MP. Survival outcomes and predictors of mortality, re-bleeding and complications for acute severe variceal bleeding requiring balloon tamponade. World J Hepatol 2022; 14(8): 1584-1597 [PMID: 36157875 DOI: 10.4254/wjh.v14.i8.1584]
Corresponding Author of This Article
Charlotte Y Keung, FRACP, MBBS, Academic Fellow, Doctor, Department of Gastroenterology, Monash Health, 246 Clayton Road, Clayton, Melbourne 3168, Victoria, Australia. charlotte.keung@monashhealth.org
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Keung CY, Morgan A, Le ST, Robertson M, Urquhart P, Swan MP. Survival outcomes and predictors of mortality, re-bleeding and complications for acute severe variceal bleeding requiring balloon tamponade. World J Hepatol 2022; 14(8): 1584-1597 [PMID: 36157875 DOI: 10.4254/wjh.v14.i8.1584]
World J Hepatol. Aug 27, 2022; 14(8): 1584-1597 Published online Aug 27, 2022. doi: 10.4254/wjh.v14.i8.1584
Survival outcomes and predictors of mortality, re-bleeding and complications for acute severe variceal bleeding requiring balloon tamponade
Charlotte Y Keung, Aparna Morgan, Suong T Le, Marcus Robertson, Paul Urquhart, Michael P Swan
Charlotte Y Keung, Aparna Morgan, Suong T Le, Marcus Robertson, Michael P Swan, Department of Gastroenterology, Monash Health, Melbourne 3168, Victoria, Australia
Charlotte Y Keung, Paul Urquhart, Department of Gastroenterology, Eastern Health, Melbourne 3128, Victoria, Australia
Charlotte Y Keung, Suong T Le, Marcus Robertson, Department of Medicine, Monash University, Melbourne 3168, Victoria, Australia
Suong T Le, Monash Digital Therapeutics and Innovation Laboratory, Monash University, Melbourne 3168, Victoria, Australia
Author contributions: Keung C designed the study, collected and analysed data and wrote the manuscript; Morgan A collected data and wrote the manuscript; Le ST reviewed the statistical analysis and performed critical revisions of the manuscript; Robertson M performed critical revisions of the manuscript; Urquhart P performed critical revisions of the manuscript; Swan M designed and supervised the study and performed critical revisions of the manuscript.
Institutional review board statement: This study was reviewed and approved by the Monash Health Human Research Ethics Committee (RES-21-0000-218Q-70254).
Informed consent statement: Patients were not required to give informed consent to this study and the analysis used anonymous clinical data.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
STROBE statement: All authors have read the STROBE Statement checklist of items and the manuscript was prepared and revised according to the STROBE Statement checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Charlotte Y Keung, FRACP, MBBS, Academic Fellow, Doctor, Department of Gastroenterology, Monash Health, 246 Clayton Road, Clayton, Melbourne 3168, Victoria, Australia. charlotte.keung@monashhealth.org
Received: March 30, 2022 Peer-review started: March 30, 2022 First decision: June 8, 2022 Revised: June 22, 2022 Accepted: July 26, 2022 Article in press: July 26, 2022 Published online: August 27, 2022 Processing time: 148 Days and 21.9 Hours
Core Tip
Core Tip: Acute severe variceal bleeding requiring balloon tamponade remains associated with high mortality rates of approximately 50%. Sengstaken-Blakemore tube achieves excellent primary haemostasis rates in > 90% however re-bleeding is common at approximately 30% with subsequent death in approximately 75%. Predictors of all-cause mortality at 6 wk included a greater Model for Endstage Liver disease score, re-bleeding and advanced hepatocellular carcinoma. The most commonly reported complication from SBT was mucosal trauma, which was conservatively managed, with only a small proportion resulting in serious complications (6.3%). There was significant variability amongst technical aspects of balloon tamponade insertion which may result from the infrequent need to perform this procedure.
