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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 27, 2022; 14(5): 911-922
Published online May 27, 2022. doi: 10.4254/wjh.v14.i5.911
Published online May 27, 2022. doi: 10.4254/wjh.v14.i5.911
Loco-regional treatment of hepatocellular carcinoma: Role of contrast-enhanced ultrasonography
Agostino Inzerillo, Adele Taibbi, Tommaso Vincenzo Bartolotta, Department of Radiology, University Hospital "Paolo Giaccone", Palermo 90127, Italy
Maria Franca Meloni, Department of Radiology, Casa di Cura Igea, Milan 20121, Italy
Tommaso Vincenzo Bartolotta, Department of Radiology, Fondazione Istituto G. Giglio Hospital, Cefalù 90015, Italy
Author contributions: Inzerillo A, Meloni MF, Taibbi A and Bartolotta TV contributed equally to this work; all authors have read and approved the final manuscript.
Conflict-of-interest statement: Tommaso Vincenzo Bartolotta: Lecturer for Samsung.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tommaso Vincenzo Bartolotta, MD, PhD, Full Professor, Director, Professor, Department of Radiology, University Hospital "Paolo Giaccone", Via del Vespro 129, Palermo 90127, Italy. tommasovincenzo.bartolotta@unipa.it
Received: February 25, 2021
Peer-review started: February 25, 2021
First decision: May 13, 2021
Revised: May 26, 2021
Accepted: April 20, 2022
Article in press: April 20, 2022
Published online: May 27, 2022
Processing time: 452 Days and 13 Hours
Peer-review started: February 25, 2021
First decision: May 13, 2021
Revised: May 26, 2021
Accepted: April 20, 2022
Article in press: April 20, 2022
Published online: May 27, 2022
Processing time: 452 Days and 13 Hours
Core Tip
Core Tip: Contrast enhanced ultrasound (CEUS) is playing an increasingly important role to evaluate locoregional treatments efficacy in hepatocellular carcinoma. In this paper, on the basis of personal experience and the relevant literature, we will review and discuss the CEUS technique. We will also highlight the importance of CEUS in evaluating the efficacy and post-procedural surveillance and their efficacy compared to the gold standard contrast-enhanced computed tomography and contrast-enhanced magnetic resonance imaging.