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World J Hepatol. Jan 27, 2022; 14(1): 45-61
Published online Jan 27, 2022. doi: 10.4254/wjh.v14.i1.45
Current aspects of renal dysfunction after liver transplantation
Mariana P Pacheco, Luiz Augusto Carneiro-D'Albuquerque, Daniel F Mazo
Mariana P Pacheco, Daniel F Mazo, Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, University of São Paulo School of Medicine, Sao Paulo 05403-900, Sao Paulo, Brazil
Luiz Augusto Carneiro-D'Albuquerque, Division of Digestive Organs Transplant, Department of Gastroenterology, University of São Paulo School of Medicine, Sao Paulo 05403-900, Sao Paulo, Brazil
Daniel F Mazo, Division of Gastroenterology, Department of Internal Medicine, School of Medical Sciences of University of Campinas, Campinas 13083-878, Sao Paulo, Brazil
Author contributions: Pacheco MP and Mazo DF conceived the idea, conducted the literature review, and wrote the manuscript; Carneiro-D'Albuquerque LA critically reviewed the manuscript; and all authors approved the final version of the manuscript for publication.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Daniel F Mazo, MD, PhD, Professor, Staff Physician, Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar nº 255, Instituto Central, # 9159, Sao Paulo 05403-900, Sao Paulo, Brazil. daniel.mazo@hc.fm.usp.br
Received: February 24, 2021
Peer-review started: February 24, 2021
First decision: October 17, 2021
Revised: October 24, 2021
Accepted: January 6, 2022
Article in press: January 6, 2022
Published online: January 27, 2022
Processing time: 330 Days and 10.9 Hours
Core Tip

Core Tip: Post-liver transplantation renal dysfunction is a frequent complication that has a major impact on the survival rate of the graft and the patient. Due to the multifactorial nature of post-transplantation chronic kidney disease, the ability to accurately identify patients under risk and the development of preventive approaches are paramount. This review presents the state-of-the-art on the topic: Its causes, renal function assessment methods, and the most studied nephroprotective strategies.