©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Sep 27, 2020; 12(9): 685-692
Published online Sep 27, 2020. doi: 10.4254/wjh.v12.i9.685
Published online Sep 27, 2020. doi: 10.4254/wjh.v12.i9.685
Non-alcoholic fatty liver disease later diagnosed as myotonic dystrophy
Naoki Tanaka, Department of Metabolic Regulation, Shinshu University School of Medicine, Matsumoto 390-8621, Japan
Takefumi Kimura, Naoyuki Fujimori, Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto 390-8621, Japan
Yasuyuki Ichise, Akira Horiuchi, Digestive Disease Center, Showa Inan General Hospital, Komagane 399-4117, Japan
Kenji Sano, Department of Pathology, Iida Municipal Hospital, Iida 395-8502, Japan
Author contributions: Tanaka N, Kimura T, and Ichise Y were the patient’s physicians, reviewed the literature, and contributed to manuscript drafting; Sano K performed pathological interpretation and contributed to manuscript drafting; Fujimori N and Horiuchi A supervised the manuscript; all authors approved submission of the final version.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Naoki Tanaka, MD, PhD, Associate Professor, Department of Metabolic Regulation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. naopi@shinshu-u.ac.jp
Received: April 22, 2020
Peer-review started: April 22, 2020
First decision: May 15, 2020
Revised: July 24, 2020
Accepted: August 1, 2020
Article in press: August 1, 2020
Published online: September 27, 2020
Processing time: 152 Days and 10.2 Hours
Peer-review started: April 22, 2020
First decision: May 15, 2020
Revised: July 24, 2020
Accepted: August 1, 2020
Article in press: August 1, 2020
Published online: September 27, 2020
Processing time: 152 Days and 10.2 Hours
Core Tip
Core Tip: We describe a patient with non-alcoholic steatohepatitis (NASH) who was later diagnosed as having myotonic dystrophy (MD). Some MD patients with minimal-to-mild muscle symptoms may be misdiagnosed as having non-alcoholic fatty liver disease (NAFLD). Therefore, when gastroenterologists encounter patients with NAFLD/NASH, serum creatine kinase (CK) should be verified. If high serum CK levels persist in the presence of frontal baldness, a hatched face, history of cataract surgery, and grip myotonia, the possibility of MD may be considered.