©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2020; 12(12): 1158-1167
Published online Dec 27, 2020. doi: 10.4254/wjh.v12.i12.1158
Published online Dec 27, 2020. doi: 10.4254/wjh.v12.i12.1158
Spectrum of esophageal motility disorders in patients with liver cirrhosis
Mohamed Khalaf, Puja Sukhwani Elias, Department of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, SC 29401, United States
Donald Castell, Department of Internal Medicine, Medical University of South Carolina, Charleston, SC 29425, United States
Author contributions: Khalaf M, Castell D and Elias PS reviewed the literature and wrote the manuscript; and all authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest.
Corresponding author: Mohamed Khalaf, MD, MSc, Assistant Lecturer, Postdoctoral Fellow, Department of Gastroenterology and Hepatology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29401, United States. moh.h.khalaf@gmail.com
Received: August 1, 2020
Peer-review started: August 1, 2020
First decision: September 17, 2020
Revised: October 1, 2020
Accepted: November 6, 2020
Article in press: November 6, 2020
Published online: December 27, 2020
Processing time: 139 Days and 2.1 Hours
Peer-review started: August 1, 2020
First decision: September 17, 2020
Revised: October 1, 2020
Accepted: November 6, 2020
Article in press: November 6, 2020
Published online: December 27, 2020
Processing time: 139 Days and 2.1 Hours
Core Tip
Core Tip: (1) The link between liver cirrhosis and esophageal motility; (2) The association of cirrhosis with gastroesophageal reflux disease; (3) Esophageal motility disorders in cirrhosis patients (with and without esophageal varices); (4) The impact of variceal treatment on esophageal motility and function; (5) The impact of some etiologies of cirrhosis on esophageal motility, particularly in cases of chronic alcoholism and primary biliary cholangitis; and (6) The effect of immunosuppressive therapy used in post liver transplantation patients on esophageal motility.