©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Concise review of machine perfusion in liver transplantation
Chirag S Desai, David A Gerber, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
David A Gerber, Lineberger Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
Author contributions: Gerber DA performed the review and wrote the paper; Desai CS wrote the paper.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Corresponding author: David A Gerber, MD, Professor, Department of Surgery, University of North Carolina at Chapel Hill, CB#7211, 4025 Burnett-Womack Building, Chapel Hill, NC 27599, United States. david_gerber@med.unc.edu
Received: September 1, 2019
Peer-review started: September 1, 2019
First decision: September 20, 2019
Revised: November 21, 2019
Accepted: November 29, 2019
Article in press: November 29, 2019
Published online: January 27, 2020
Processing time: 123 Days and 6.5 Hours
Peer-review started: September 1, 2019
First decision: September 20, 2019
Revised: November 21, 2019
Accepted: November 29, 2019
Article in press: November 29, 2019
Published online: January 27, 2020
Processing time: 123 Days and 6.5 Hours
Core Tip
Core tip: The processes involved in optimizing and expanding the deceased donor liver pool has led to the incorporation of machine perfusion technologies (as is similarly done in kidney transplantation). While none of the systems is approved for clinical use, several have gone through clinical trials. This summary provides an overview of those technologies that are likely to be used in clinical liver transplantation.