©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Nov 27, 2018; 10(11): 837-848
Published online Nov 27, 2018. doi: 10.4254/wjh.v10.i11.837
Published online Nov 27, 2018. doi: 10.4254/wjh.v10.i11.837
Decision modelling for economic evaluation of liver transplantation
Zhi Qu, Christian Krauth, Volker Eric Amelung, Alexander Kaltenborn, Jill Gwiasda, Lena Harries, Jan Beneke, Harald Schrem, Sebastian Liersch, Core Facility Quality Management and Health Technology Assessment in Transplantation, Integrated Research and Treatment Facility Transplantation (IFB-Tx), Hannover Medical School, Hannover 30625, Germany
Zhi Qu, Christian Krauth, Volker Eric Amelung, Lena Harries, Sebastian Liersch, Institute for Epidemiology, Social Medicine and Health Systems Research, Hannover Medical School, Hannover 30625, Germany
Harald Schrem, General, Visceral and Transplant Surgery, Hannover Medical School, Hannover 30625, Germany
Author contributions: Qu Z, Krauth C and Schrem H conceptualized the overview. Qu Z, Gwiasda J and Liersch S drafted the manuscript. Amelung VE, Kaltenborn A, Harries L, Beneke J and Schrem H critically reviewed the manuscript and contributed important intellectual contents.
Supported by a grant from the German Federal Ministry of Education and Research , No. 01EO1302 .
Conflict-of-interest statement: The authors of this manuscript declare no conflicts of interest.
Correspondence to: Zhi Qu, PhD, Doctor, Core Facility Quality Management and Health Technology Assessment in Transplantation, Integrated Research and Treatment Facility Transplantation (IFB-Tx), Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany. qu.zhi@mh-hannover.de
Telephone: +49-511-5324453 Fax: +49-511-5325347
Received: May 25, 2018
Peer-review started: May 25, 2018
First decision: June 13, 2018
Revised: July 2, 2018
Accepted: October 9, 2018
Article in press: October 9, 2018
Published online: November 27, 2018
Processing time: 187 Days and 3.3 Hours
Peer-review started: May 25, 2018
First decision: June 13, 2018
Revised: July 2, 2018
Accepted: October 9, 2018
Article in press: October 9, 2018
Published online: November 27, 2018
Processing time: 187 Days and 3.3 Hours
Core Tip
Core tip: This overview focuses on providing an understanding of decision modelling approaches and their application to liver transplantation, outlining the major characteristics of decision analytic models as well as the individual strengths and weaknesses of several main techniques for modelling. We believe decision modelling may be able to provide tools by bringing all evidence from other studies together and comparing the costs and consequences of alternative options to reach a decision. It is a particularly powerful tool for public health policy and clinical intervention assessment.