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Kobayashi S. Importance of comprehensive nutritional assessment in predicting survival in cirrhosis. World J Hepatol 2025; 17(5): 106606 [PMID: 40501461 DOI: 10.4254/wjh.v17.i5.106606]
World J Hepatol. May 27, 2025; 17(5): 106606 Published online May 27, 2025. doi: 10.4254/wjh.v17.i5.106606
Importance of comprehensive nutritional assessment in predicting survival in cirrhosis
Shinichiro Kobayashi
Shinichiro Kobayashi, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagagasaki 852-8501, Nagasaki, Japan
Author contributions: Kobayashi S wrote the original draft and read and approved the final version of the manuscript.
Supported by Grant-in-Aid for Scientific Research C, No. 24K11935.
Conflict-of-interest statement: There are no financial or other relations that could lead to a conflict of interest regarding this study.
Corresponding author: Shinichiro Kobayashi, MD, PhD, Assistant Professor, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Ohmura, Nagagasaki 852-8501, Nagasaki, Japan. skobayashi1980@gmail.com
Received: March 4, 2025 Revised: March 20, 2025 Accepted: April 2, 2025 Published online: May 27, 2025 Processing time: 86 Days and 4.9 Hours
Abstract
Carteri et al reaffirmed the value of the Child-Turcotte-Pugh score in predicting survival in patients with cirrhosis. However, the lack of association with nutritional markers warrants careful interpretation. In cirrhosis, complex conditions often lead to malnutrition and individual markers may not be fully captured. Comprehensive assessments such as Subjective Global Assessment, handgrip strength, muscle mass measurements, and bioelectrical impedance analysis can improve risk stratification and inform personalized nutritional management. This letter emphasizes the need for standardized nutritional assessments for patients with cirrhosis and further research to clarify their impact on long-term outcomes, potentially improving patient care.
Core Tip: Carteri et al highlighted the role of the Child-Turcotte-Pugh score in cirrhosis prognosis but neglected comprehensive nutrition. This letter emphasizes standardized tools such as Subjective Global Assessment and bioelectrical impedance analysis for risk assessment and hepatic encephalopathy management. We advocate longitudinal studies and multidisciplinary care to improve outcomes, particularly post-transplantation outcomes.
