Published online Dec 27, 2023. doi: 10.4254/wjh.v15.i12.1338
Peer-review started: September 13, 2023
First decision: October 16, 2023
Revised: October 21, 2023
Accepted: November 29, 2023
Article in press: November 29, 2023
Published online: December 27, 2023
Processing time: 102 Days and 15.4 Hours
Strongyloides sterocoralis is a parasitic infection caused by a roundworm that is transmitted through soil contaminated with larvae. It can infrequently cause hepatic abscesses in immunocompromised patients and is rarely reported to form hepatic lesions in immunocompetent hosts.
We present a case study of a 45-year-old female who presented with right upper quadrant abdominal pain and constitutional symptoms for several weeks. Cross-sectional imaging identified several malignant-appearing liver masses. Further investigation, including serological testing and histopathologic examination, revealed the presence of serum Strongyloides antibodies and hepatic granulomas with extensive necrosis. Following treatment with ivermectin for 2 wk, there was complete resolution of the liver lesions and associated symptoms.
This case highlights the importance of considering parasitic infections, such as Strongyloides, in the differential diagnosis of hepatic masses. Early recognition and appropriate treatment can lead to a favorable outcome and prevent unnecessary invasive procedures. Increased awareness among clinicians is crucial to ensure the timely diagnosis and management of such cases.
Core Tip: Hepatic pseudotumor is a clinical entity that can mimic malignant tumors of the liver. We report a rare case of hepatic pseudotumor caused by Strongyloides sterocoralis. Combined with a review of cases indexed in PubMed, we summarize the infectious causes of hepatic pseudotumor. Recognition of hepatic mass-forming parasitic infections may expedite prompt medical management.