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Nov 26, 2011 (publication date) through Nov 18, 2025
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World Journal of Stem Cells
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1948-0210
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright ©2011 Baishideng Publishing Group Co.
World J Stem Cells. Nov 26, 2011; 3(11): 96-103
Published online Nov 26, 2011. doi: 10.4252/wjsc.v3.i11.96
Table 1 Mesenchymal stem cells as cellular vehicles for targeting cancer
Anticancer agentAnticancer mechanismTumor modelRoute of MSC admi-nistrationSpecies: MSC/tumor/hostRef.
CX3CL1ImmunostimulatoryLungivMouse/mouse/mouse[40]
CDProdrug convertingProstatesc/ivHuman/human/mouse[41]
Colonsc/ivHuman/human/mouse[14]
HSV-tkGliomaitRat/rat/rat[42]
PancreasivMouse/mouse/mouse[28]
IFNαImmunostimulatory and apoptosis indcingMelanomaivMouse/mouse/mouse[43]
Gliomait/icMouse/mouse/mouse[44]
IFNβBreastsc/ivHuman/human/mouse[29,45]
PancreasipHuman/human/mouse[27]
IL2Gliomait/icRat/rat/rat[17]
IL7ImmunostimulatoryGliomaitRat/rat/rat[46]
IL12Activates cytotoxic lymphocyte and NK cellsMelanomaivMouse/mouse/mouse[47]
HepatomaivMouse/mouse/mouse[47]
BreastivMouse/mouse/mouse[47]
IL18ImmunostimulatoryGliomaitRat/rat/rat[48]
NK4Inhibits angiogenesisColonivMouse/mouse/mouse[49]
TRAILInduces apoptosisGliomaitHuman/human/mouse[20]
GliomaicHuman/human/mouse[50]
GliomaivHuman/human/mouse[22,51]
LungivHuman/human/mouse[52]
Breast, lungsc/ivHuman/human/mouse[53]
ColonscHuman/human/mouse[54,55]
PancreasivHuman/human/mouse[56]
CD: Cytosine deaminase; CX3CL1: Chemokine fractalkine; HSV-tk: Herpes simplex virus-thymidine kinase; ic: Intracerebral; IFN: Interferon; IL: Interleukin; ip: Intraperitoneal; it: Intratumoral; iv: Intravenous; NK: Natural killer; sc: Subcutaneous; TRAIL: Tumor necrosis factor-related apoptosis-inducing ligand.
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