Tongxie Yaofang enhances the homing efficiency of exogenous bone marrow-derived mesenchymal stem cells to the colonic mucosa and alleviates ulcerative colitis

Table 1 The components and major bioactive components of Tongxie Yaofang

Herb name	Latin name	Major bioactive compounds
Baizhu	Atractylodes macrocephala Koidz.	Atractylenolide I, II, III
Baishao	Paeoniae Radix Alba	Paeoniflorin
Chenpi	Citri Reticulatae Pericarpium	Hesperidin
Fangfeng	Saposhnikovia divaricate	5-O-methylvisamminol and cimifugin

Table 2 Oligonucleotides used for real-time quantitative polymerase chain reaction

Gene	Direction	Sequence
β-actin	Forward	CTAAGGCCAACCGTGAAAAG
	Reverse	AACACAGCCTGGATGGCTAC
SDF-1	Forward	GCCCTTCAGATTGTTGCAAGGC
	Reverse	TGGGCTGTTGTGCTTACTTGT
CXCR-4	Forward	TCTGAGGCGTTTGGTGCTC
	Reverse	GTTTTCATCCCGGAAGCAGG
Claudin-4	Forward	TTTTCGTGCTCCCCAACCTT
	Reverse	ATGGGGAGCGAACAACTCAG
ZO-1	Forward	GATGTTTATGCGGACGGTGG
	Reverse	CATTGCTGTGCTCTTAGCGG
TNF-α	Forward	GATCGGTCCCAACAAGGAGG
	Reverse	CTTGGTGGTTTGCTACGACG
IL-6	Forward	CACTTCACAAGTCGGAGGCT
	Reverse	GAATTGCCATTGCACAACTCT
IL-1β	Forward	CAGCTTTCGACAGTGAGGAGA
	Reverse	TGTCGAGATGCTGCTGTGAG

SDF-1: Stromal cell-derived factor 1; CXCR-4: C-X-C chemokine receptor type 4; ZO-1: Zonula occludens-1; TNF-α: Tumor necrosis factor-α; IL: Interleukin.