Single-cell RNA sequencing in cornea research: Insights into limbal stem cells and their niche regulation

doi:10.4252/wjsc.v15.i5.466

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 5

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3047)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-1) series.

Item

Count

PDF

144

WORD

HTML

1657

Figures (1-3)

134

Tables (1-1)

163

Sum=2120

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

151

Download

484

Sum=635

Publishing Process of This Article

Item

Count

Browse

100

Download

192

Sum=292

May 26, 2023 (publication date) through Nov 24, 2024

Times Cited of This Article

Times Cited (4)

Journal Information of This Article

Publication Name

World Journal of Stem Cells

ISSN

1948-0210

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Stem Cells. May 26, 2023; 15(5): 466-475
Published online May 26, 2023. doi: 10.4252/wjsc.v15.i5.466

Table 1 Novel limbal stem cell markers identified by single-cell RNA sequencing

LSC subtype	Marker	Species	Ref.
LSPC with high stemness	TP63, CCL20	Human	[43]
LSPC with high differentiation	GPHA2, KRT6B	Human	[43]
LSC	TSPAN7, SOX17, SELE, ECSCR, RAMP3, RNASE1, NPCD1, NNMT, SLC2A3, KLF2, PDK4	Human	[49]
Limbal progenitor cell	DCN, PLIN2, DEGS1, MMP10, IFITM3, SLC6A6, LTB4R, SLP1	Human	[49]
qLSC	Gpha2, Cd63, Ifitm3	Mouse	[46]
aLSC	Atf3, Socs3, Mt1, Prdm1	Mouse	[46]

aLSC: Active limbal stem cell; LSC: Limbal stem cell; LSPC: Limbal stem/progenitor cell; qLSC: Quiescent limbal stem cell.

Citation: Sun D, Shi WY, Dou SQ. Single-cell RNA sequencing in cornea research: Insights into limbal stem cells and their niche regulation. World J Stem Cells 2023; 15(5): 466-475
URL: https://www.wjgnet.com/1948-0210/full/v15/i5/466.htm
DOI: https://dx.doi.org/10.4252/wjsc.v15.i5.466