Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain

doi:10.4252/wjsc.v15.i4.196

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Apr 26, 2023; 15(4): 196-208
Published online Apr 26, 2023. doi: 10.4252/wjsc.v15.i4.196

Table 1 Recommended therapies for the management of osteoarthritis by the American College of Rheumatology and Arthritis Foundation

	Hand	Knee	Hip
Physical and psychosocial approaches
Exercise¹	√	√	√
Self-Efficacy and Self-Management Programs¹	√	√	√
Weight loss¹		√	√
Tai Chi¹		√	√
Heat, therapeutic cooling²	√	√	√
Cognitive Behavioral Therapy²	√	√	√
Acupuncture²	√	√	√
Paraffin²	√
Yoga²		√
Pharmacological approach
Oral NSAIDs¹	√	√	√
Topical NSAIDs	√²	√¹
IA corticosteroids	√²	√¹	√¹ (image-guided)
Acetaminophen²	√	√	√
Tramadol²	√	√	√
Duloxetine²	√	√	√
Chondroitin²	√
Topical capsaicin²		√

¹Strongly recommended.

²Conditionally recommended.

Strongly and conditionally recommended approaches for the management of hand, knee, and hip osteoarthritis are shown. NSAIDs: Nonsteroidal anti-inflammatory drugs; IA: Intra-articular.

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Citation: Almahasneh F, Abu-El-Rub E, Khasawneh RR. Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain. World J Stem Cells 2023; 15(4): 196-208
URL: https://www.wjgnet.com/1948-0210/full/v15/i4/196.htm
DOI: https://dx.doi.org/10.4252/wjsc.v15.i4.196

Almahasneh F, Abu-El-Rub E, Khasawneh RR. Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain. World J Stem Cells 2023; 15(4): 196-208 [PMID: 37181003 DOI: 10.4252/wjsc.v15.i4.196]

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