Malaria modeling: In vitro stem cells vs in vivo models

Figure 1 Chart of the different stem cells used for Plasmodium in vitro modeling and their applications. Scheme of the different sources of stem cells used for liver and blood cycles of Plasmodium falciparumin vitro studies. The main aims of each study are indicated on the right.

Figure 2 Chart of the different combinations animal model/human Plasmodia for in vivo studies. Scheme of the different animal models coupled with human Plasmodium studies. The different cell types injected within humanized mice are indicated in the column “Humanized system generation” and the Plasmodium injection mode under the column “Parasite infection”.