Copyright
©The Author(s) 2015.
World J Stem Cells. Apr 26, 2015; 7(3): 583-595
Published online Apr 26, 2015. doi: 10.4252/wjsc.v7.i3.583
Published online Apr 26, 2015. doi: 10.4252/wjsc.v7.i3.583
Figure 1 Roles of Hox genes in the organisms and the cell[135-140].
Figure 2 Major signaling pathways involved in Hox gene expression.
Predominantly posterior 5’Hox genes are activated by BMP and Wnt signaling. Hox genes closer to the 3’ end of a chromosome, which are mainly expressed anteriorly, are activated by retinoic acid pathways[120,141-150]. BMP: Bone morphogenic protein; RARE: Retinoic acid response element.
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Citation: Seifert A, Werheid DF, Knapp SM, Tobiasch E. Role of
Hox genes in stem cell differentiation. World J Stem Cells 2015; 7(3): 583-595 - URL: https://www.wjgnet.com/1948-0210/full/v7/i3/583.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v7.i3.583