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World J Stem Cells. Jan 26, 2013; 5(1): 9-25
Published online Jan 26, 2013. doi: 10.4252/wjsc.v5.i1.9
Published online Jan 26, 2013. doi: 10.4252/wjsc.v5.i1.9
Figure 1 Embryonic stem cells control vs ciclopirox olamine treated cells.
Overlay of 2-DE gels of samples from ciclopirox olamine treated embryonic stem cells (ESCs) (orange) compared to control ESCs (blue). The identified proteins are indicated with the gene names.
Figure 2 Multipotent adult germline stem cells control vs ciclopirox olamine treated cells.
Overlay of 2-DE gels of samples from ciclopirox olamine treated multipotent adult germline stem cells (maGSCs) (orange) compared to control maGSCs (blue). The identified proteins are indicated with the gene names.
Figure 3 Embryonic stem cell control vs ciclopirox olamine treated cells.
Overlay of 2-DE gels of samples from ciclopirox olamine treated embryonic stem cells (ESCs) (orange) compared to retinoic acid treated ESCs (blue). The identified proteins are indicated with the gene names.
Figure 4 Multipotent adult germline stem cell control vs ciclopirox olamine treated cells.
Overlay of 2-DE gels of samples from ciclopirox olamine treated Multipotent adult germline stem cells (maGSCs) (orange) compared to retinoic acid treated maGSCs (blue). The identified proteins are indicated with the gene names.
Figure 5 Molecular function.
Classification of the downregulated proteins upon treatment with ciclopirox olamine (CPX) (A) or retinoic acid (RA) (B) according to their molecular functions.
Figure 6 Biological process.
Classification of the downregulated proteins upon treatment with ciclopirox olamine (CPX) (A) or retinoic acid (RA) (B) according to their biological processes.
Figure 7 Biological process.
Classification of the differently regulated proteins upon treatment with ciclopirox olamine (CPX) (A) or retinoic acid (RA) (B) according to their biological processes.
Figure 8 Enlargement of the gel spots of some proteins of interest.
ESC: Embryonic stem cell; maGSC: Multipotent adult germline stem cell; CPX: Ciclopirox olamine; RA: Retinoic acid.
- Citation: Dihazi GH, Bibi A, Jahn O, Nolte J, Mueller GA, Engel W, Dihazi H. Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome. World J Stem Cells 2013; 5(1): 9-25
- URL: https://www.wjgnet.com/1948-0210/full/v5/i1/9.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v5.i1.9