Stem/progenitor cell-driven immune microenvironment remodeling in sepsis-associated acute respiratory distress syndrome

Figure 1 Comparison of surfactant protein C/epithelial cell adhesion molecule/CD44 expression (violin plot). A: Relative expression of surfactant protein C; B: Proportion of epithelial cell adhesion molecule positive cells; C: Proportion of CD44 positive cells. STTPC: Surfactant protein C; EPCAM: Epithelial cell adhesion molecule.

Figure 2 Distribution of immune microenvironment indicators (violin plot). Th17: T helper 17 cell; Treg: Regulatory T cells; IL: Interleukin; TNF-α: Tumor necrosis factor-α.

Figure 3 Heat plot of correlation between epithelial progenitor cell indicators and immune/metabolic index. ^bP < 0.01. AEC II: Alveolar epithelial type II cells; STTPC: Surfactant protein C; EPCAM: Epithelial cell adhesion molecule.

Figure 4 The 28-day survival curve or outcome comparison by surfactant protein C. STTPC: Surfactant protein C; ARDS: Acute respiratory distress syndrome.