Future perspectives on mesenchymal stromal cell-derived secretomes in knee osteoarthritis

doi:10.4252/wjsc.v18.i4.117271

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Apr 26, 2026 (publication date) through Apr 22, 2026

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Apr 26, 2026; 18(4): 117271
Published online Apr 26, 2026. doi: 10.4252/wjsc.v18.i4.117271

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Figure 1 Key therapeutic effects of mesenchymal stromal cell-derived secretomes in knee osteoarthritis. MSC: Mesenchymal stromal cell.

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Figure 2 Steps involved in the quality control of secretomes containing extracellular vesicles. MISEV: Minimal Information for Studies of Extracellular Vesicles; NTA: Nanoparticle tracking analysis; RPS: Resistive pulse sensing; EVs: Extracellular vesicles.

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Figure 3 Mechanisms of engineering extracellular vesicle containing secretomes for targeted action. EVs: Extracellular vesicles.

Citation: Muruganandam A, Jeyaraman N, Sukumaran AM, Ramasubramanian S, Devanand V, Nallakumarasamy A, Muthu S, Jeyaraman M. Future perspectives on mesenchymal stromal cell-derived secretomes in knee osteoarthritis. World J Stem Cells 2026; 18(4): 117271
URL: https://www.wjgnet.com/1948-0210/full/v18/i4/117271.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i4.117271