L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies

doi:10.4252/wjsc.v17.i8.111497

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Aug 26, 2025 (publication date) through Aug 21, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Aug 26, 2025; 17(8): 111497
Published online Aug 26, 2025. doi: 10.4252/wjsc.v17.i8.111497

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Figure 1 L-arginine: A promising metabolite in enhancing the protective effects of adipose tissue-derived mesenchymal stem cells against ischemic pathologies. The metabolite L-arginine, enriched in adipose tissue-derived mesenchymal stem cells obtained from elderly patients, may enhance the therapeutic efficacy of adipose tissue-derived mesenchymal stem cells in ischemic conditions through multiple mechanisms, including promoting angiogenesis and inhibiting cell apoptosis. The schematic model was plotted with BioRender (https://www.biorender.com).

Citation: Liu N, Wan XX, Yan WT, Xiong K. L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies. World J Stem Cells 2025; 17(8): 111497
URL: https://www.wjgnet.com/1948-0210/full/v17/i8/111497.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i8.111497