Pancreatic cancer stem cells: Perspectives on potential therapeutic approaches of pancreatic ductal adenocarcinoma

doi:10.4252/wjsc.v10.i11.172

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Nov 26, 2018; 10(11): 172-182
Published online Nov 26, 2018. doi: 10.4252/wjsc.v10.i11.172

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Figure 1 Mechanism of action of different non-cancer related drugs against pancreatic cancer stem cells. EMT: Epithelial mesenchymal transition; ALDH1: Aldehyde dehydrogenase 1; NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells; mTOR: Mammalian target of rapamycin; PI3K: Phosphatidylinositol 3-kinase; Akt: Protein kinase B; OXPHOS: Oxidative phosphorylation.

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Figure 2 The types of nanoparticles. A: Different types of nanoparticles for targeted drug delivery; B: Specific nanoparticles for targeting pancreatic cancer stem cells. PCSCs: Pancreatic cancer stem cells.

Citation: Di Carlo C, Brandi J, Cecconi D. Pancreatic cancer stem cells: Perspectives on potential therapeutic approaches of pancreatic ductal adenocarcinoma. World J Stem Cells 2018; 10(11): 172-182
URL: https://www.wjgnet.com/1948-0210/full/v10/i11/172.htm
DOI: https://dx.doi.org/10.4252/wjsc.v10.i11.172