Mallis P. Hypoxic endometrial epithelial cell-derived microRNAs effectively regulate the regenerative properties of mesenchymal stromal cells. World J Stem Cells 2025; 17(4): 102482 [PMID: 40308881 DOI: 10.4252/wjsc.v17.i4.102482]
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03947685
Submitted on:
May 01, 2025, 11:18
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Reader Comments:
A letter to the Editor entitled Hypoxic endometrial epithelial cell-derived microRNAs effectively regulate the regenerative properties of mesenchymal stromal cells by Dr Mallis elegantly comments on the significance of the study published by Dr Zhang. The author highlights the clinical significance of the data obtained from in vitro experiments and, at the same time, provides mechanistic insight into the role of mir-214-5p and 21-5p in mesenchymal stem cells’ functionality and reparability of endometrial endothelial cells. The author has rightfully suggested that the published data by Zhang et al. has been derived from in vitro experimentation and there is a need for supporting this data by in vivo experiments. The letter is fluently written and supplements the findings of Zhang et al.
Reply from the Editorial Office:
Thank you very much for your comments.