Hsiao HY, Nien CY, Hong HH, Cheng MH, Yen TH. Application of dental stem cells in three-dimensional tissue regeneration. World J Stem Cells 2021; 13(11): 1610-1624 [PMID: 34909114 DOI: 10.4252/wjsc.v13.i11.1610]
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03813519
Submitted on:
November 30, 2021, 04:55
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Reader Comments:
In this review article, Hsiao et.al. summarized the current advancement in the use of 3D technology to differentiate dental pulp stem cells. The application of 3D conditions has been successfully used in stem cells isolated different sources including human embryonic stem cells (hESCs) and the induced pluripotent stem cells (iPSCs). 3D-mediated stem cells differentiation creates a microenvironment that mimics the in vivo situation, improves cell-cell contact, and enhances cell signaling.
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