| For: | Jiang LL, Liu L. Effect of metformin on stem cells: Molecular mechanism and clinical prospect. World J Stem Cells 2020; 12(12): 1455-1473 [PMID: 33505595 DOI: 10.4252/wjsc.v12.i12.1455] |
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| URL: | https://www.wjgnet.com/1948-0210/full/v12/i12/1455.htm |
| Number | Citing Articles |
| 1 |
Raheleh Pourpirali, Aydin Mahmoudnezhad, Fatemeh Oroojalian, Nosratollah Zarghami, Younes Pilehvar. Prolonged proliferation and delayed senescence of the adipose-derived stem cells grown on the electrospun composite nanofiber co-encapsulated with TiO2 nanoparticles and metformin-loaded mesoporous silica nanoparticles. International Journal of Pharmaceutics 2021; 604 doi: 10.1016/j.ijpharm.2021.120733
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| 2 |
Sara Cruciani, Giuseppe Garroni, Renzo Pala, Maria Laura Cossu, Giorgio Carlo Ginesu, Carlo Ventura, Margherita Maioli. Metformin and Vitamin D Modulate Inflammation and Autophagy during Adipose-Derived Stem Cell Differentiation. International Journal of Molecular Sciences 2021; 22(13) doi: 10.3390/ijms22136686
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| 3 |
Sereen K. Nashif, Renee M. Mahr, Snehalata Jena, Seokwon Jo, Alisa B. Nelson, Danielle Sadowski, Peter A. Crawford, Patrycja Puchalska, Emilyn U. Alejandro, Micah D. Gearhart, Sarah A. Wernimont. Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner. Frontiers in Cell and Developmental Biology 2023; 11 doi: 10.3389/fcell.2023.1167097
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| 4 |
Lidija Križančić Bombek, Maša Čater. Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity. Metabolites 2022; 12(3) doi: 10.3390/metabo12030259
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| 5 |
Yi Zhang, Fang Zhou, Jiaheng Guan, Lukun Zhou, Baoan Chen. Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review. Biomolecules 2023; 13(2) doi: 10.3390/biom13020250
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| 6 |
Mahmoud T El-Destawy, AbdelAziz AKA AboAmo, Mahetab M Abdel-Wahab, Mostafa M Hosny, Ahmed M Bilal, Samy Saeed, Abd el-latif G Borhamy, Ahmed M Elshamy, Ahmed Halim, Aya Ali Hussien. Evaluation of Horizontal Ridge Augmentation Using 1% Metformin Gel and PRF in Split Crest Technique: A Randomized Controlled Clinical Trial. The Journal of Contemporary Dental Practice 2025; 26(8) doi: 10.5005/jp-journals-10024-3921
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| 7 |
Cordell A. VanGenderen, Jules A. Granet, Romina L. Filippelli, Yiyang Liu, Natasha C. Chang. Modulating Myogenesis: An Optimized In Vitro Assay to Pharmacologically Influence Primary Myoblast Differentiation. Current Protocols 2022; 2(9) doi: 10.1002/cpz1.565
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| 8 |
Zi Ye, Shanshan Chen, Jiali Rui, Lumin Tang, Tianshi Wang, Qiuju Fan. Multi-layered regulatory mechanisms and translational implications of mitochondrial redox imbalance in aging stem cells. Free Radical Biology and Medicine 2026; 254 doi: 10.1016/j.freeradbiomed.2026.06.038
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| 9 |
Bauyrzhan Umbayev, Yuliya Safarova, Aislu Yermekova, Timur Saliev. Nutrition, Food and Diet in Ageing and Longevity. Healthy Ageing and Longevity 2021; 14 doi: 10.1007/978-3-030-83017-5_25
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| 10 |
Ebru Goncu. Autophagy in Stem Cell Maintenance and Differentiation. Stem Cell Biology and Regenerative Medicine 2023; 73 doi: 10.1007/978-3-031-17362-2_7
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| 11 |
Xiaoping Tan, Ying Yan, Gengrong Zhang, Pengfei Li, Fei Ling, Tianqiang Liu, Gaoxue Wang. Target epidermal damage of Gyrodactylus kobayashii to obtain the effective anthelmintic compound glacial acetic acid. Aquaculture 2023; 577 doi: 10.1016/j.aquaculture.2023.739993
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| 12 |
Faraz Radmand, Milad Baseri, Maryam Farsadbakhsh, Ayub Azimi, Solmaz Maleki Dizaj, Simin Sharifi. A Novel Perspective on Tissue Engineering Potentials of Periodontal Ligament Stem Cells. The Open Dentistry Journal 2022; 16(1) doi: 10.2174/18742106-v16-e221006-2021-216
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| 13 |
Zeqing Zhao, Qingchen Qiao, Yaxi Sun, Jing Wang, Xiaowei Li, Li Zhang, Hao Yang, Ke Zhang, Ning Zhang, Yuxing Bai. Human periodontal ligament stem cells and metformin to enhance periodontal regeneration in rats. Journal of Dentistry 2025; 156 doi: 10.1016/j.jdent.2025.105700
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| 14 |
Pingting Ye, Lei Feng, Dan Zhang, Ruihao Li, Yixuan Wen, Xiaohan Tong, Shuo Shi, Chunyan Dong, Federico Mussano. Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy. Stem Cells International 2023; 2023 doi: 10.1155/2023/1429642
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| 15 |
Caifeng Li, Zhao Cui, Shiwen Deng, Peng Chen, Xianyu Li, Hongjun Yang. The potential of plant extracts in cell therapy. Stem Cell Research & Therapy 2022; 13(1) doi: 10.1186/s13287-022-03152-z
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| 16 |
Sashana Dixon, Ann Tenneil O’connor, Chloe Brooks-Noreiga, Michelle A. Clark, Arkene Levy, Ana M. Castejon. Role of renin angiotensin system inhibitors and metformin in Glioblastoma Therapy: a review. Cancer Chemotherapy and Pharmacology 2024; 94(1) doi: 10.1007/s00280-024-04686-0
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| 17 |
Samar A. Antar, Marwa Abd-Elsalam, Walied Abdo, Ahmed Abdeen, Mohamed Abdo, Liana Fericean, Nahed A. Raslan, Samah F. Ibrahim, Asmaa F. Sharif, Amira Elalfy, Hend E. Nasr, Ahmed B. Zaid, Rania Atia, Ahmed M. Atwa, Mohammed A. Gebba, Amany A. Alzokaky. Modulatory Role of Autophagy in Metformin Therapeutic Activity toward Doxorubicin-Induced Nephrotoxicity. Toxics 2023; 11(3) doi: 10.3390/toxics11030273
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| 18 |
Flávio Kiyoshi Tominaga, Juliana Mendonça Silva de Jesus, Natalia Klanovicz, Marcelo Miyada Redígolo, Thalita Tieko Silva, Daniel Temponi Lebre, Antonio Carlos Silva Costa Teixeira, Patricia Leo, Sueli Ivone Borrely. Ecotoxicological assessment of metformin as an antidiabetic water residue treated by electron beam accelerator irradiation. Discover Water 2024; 4(1) doi: 10.1007/s43832-023-00053-x
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| 19 |
Kathrin Kahnert, Stefan Andreas, Christina Kellerer, Johanna I. Lutter, Tanja Lucke, Önder Yildirim, Mareike Lehmann, Jochen Seissler, Jürgen Behr, Marion Frankenberger, Robert Bals, Henrik Watz, Tobias Welte, Franziska C. Trudzinski, Claus F. Vogelmeier, Peter Alter, Rudolf A. Jörres, Stefan Andreas, Robert Bals, Jürgen Behr, Kathrin Kahnert, Thomas Bahmer, Burkhard Bewig, Ralf Ewert, Beate Stubbe, Joachim H. Ficker, Christian Grohé, Matthias Held, Markus Henke, Felix Herth, Anne-Marie Kirsten, Henrik Watz, Rembert Koczulla, Juliane Kronsbein, Cornelia Kropf-Sanchen, Christian Herzmann, Michael Pfeifer, Winfried J. Randerath, Werner Seeger, Michael Studnicka, Christian Taube, Hartmut Timmermann, Peter Alter, Bernd Schmeck, Claus Vogelmeier, Tobias Welte, Hubert Wirtz. Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment. Scientific Reports 2022; 12(1) doi: 10.1038/s41598-022-05276-x
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| 20 |
Zelong Zhao, Dandan Yin, Kexin Yang, Chunmei Zhang, Linxia Song, Zhenbiao Xu. Transcriptome Sequencing Analysis of the Effects of Metformin on the Regeneration of Planarian Dugesia japonica. Genes 2025; 16(4) doi: 10.3390/genes16040365
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| 21 |
Shangze Jiang, Qingjun Lu. A new contribution for an old drug. Journal of Cancer Research and Therapeutics 2021; 17(7) doi: 10.4103/jcrt.jcrt_1824_21
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| 22 |
Sara S Nabavizadeh, Mehri Shadi, Mohammadhossein Khorraminejad-Shirazi, Sajad Daneshi, Saeid Tavanafar, Reyhaneh Naseri, Alireza Abbaspour, Keivan Alaei-Jahromi, Tahereh Talaei-Khozani. Moldable Alginate/Hydroxyapatite Hydrogel Loaded with Metformin Enhanced Regeneration of the Rabbit Mandibular Defects. Journal of Maxillofacial and Oral Surgery 2024; 23(6) doi: 10.1007/s12663-023-02094-0
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| 23 |
Francisco Sotomayor-Lugo, Nataly Iglesias-Barrameda, Imilla Casado-Hernandez, Carlos Agustin Villegas-Valverde, Yendry Ventura-Carmenate, Rene Antonio Rivero-Jimenez. Aging: Disease or “natural” process? A glimpse from regenerative medicine. Revista Española de Geriatría y Gerontología 2025; 60(1) doi: 10.1016/j.regg.2024.101543
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| 24 |
Pejman Kokhabi, Sahar Dadkhahfar, Reza M. Robati. Topical metformin as a novel therapy for alopecia areata due to its immunologic effects. Medical Hypotheses 2023; 179 doi: 10.1016/j.mehy.2023.111155
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| 25 |
Fatemeh Karami, Hamidreza Jamaati, Natalie Coleman-Fuller, Maryam Shokrian Zeini, A. Wallace Hayes, Mina Gholami, Mahsa Salehirad, Mohammad Darabi, Majid Motaghinejad. Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis. Pharmacological Reports 2023; 75(3) doi: 10.1007/s43440-023-00469-1
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| 26 |
Tongpeng Yue, Deguan Li. Senescent Stem Cell Dysfunction and Age-Related Diseases. Stem Cells and Development 2023; 32(19-20) doi: 10.1089/scd.2023.0065
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| 27 |
Alessia Greco, Francesca Coperchini, Laura Croce, Flavia Magri, Marsida Teliti, Mario Rotondi. Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs. Frontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1303844
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| 28 |
Norma Lopez, Sara M. Cohen, Maryann Emanuele. Type 2 Diabetes and Bone Disease. Clinical Reviews in Bone and Mineral Metabolism 2023; 21(1-4) doi: 10.1007/s12018-023-09288-7
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| 29 |
Nataya Sritawan, Apiwat Sirichoat, Anusara Aranarochana, Wanassanan Pannangrong, Peter Wigmore, Jariya Umka Welbat. Protective effect of metformin on methotrexate induced reduction of rat hippocampal neural stem cells and neurogenesis. Biomedicine & Pharmacotherapy 2023; 162 doi: 10.1016/j.biopha.2023.114613
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| 30 |
Banu Turhan, Sönmez Sağlam, Mücahit Osman Yücel, Raşit Emin Dalaslan, Mehmet Ali Sungur, Fatih Demir, Zekeriya Okan Karaduman, Mehmet Arıcan. The effects of liraglutide and metformin treatment on fracture healing in partially insulinopenic diabetic rats. Frontiers in Endocrinology 2025; 16 doi: 10.3389/fendo.2025.1703958
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| 31 |
Nada G. Hamam, Mahmoud Samir, Nereen A. Almosilhy, Mohamad Mahmoud Whdan, Omar A. Mohamed, Mohamed Mohsen Helal. Metformin as a Neoadjuvant to Chemotherapy in Locally Advanced and Metastatic Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Clinical Breast Cancer 2026; doi: 10.1016/j.clbc.2026.07.017
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| 32 |
Eleonora Maniscalco, Giuliana Abbadessa, Magalì Giordano, Loredana Grasso, Paolo Borrione, Silvia Racca, Antonio Musaro. Metformin regulates myoblast differentiation through an AMPK-dependent mechanism. PLOS ONE 2023; 18(2) doi: 10.1371/journal.pone.0281718
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| 33 |
Elisabetta Mormone, Vittoria D’Esposito, Paola De Luca, Fulvio E. O. Ferrara, Francesca P. Bellotti, Pietro Formisano, Eugenio Caradonna. Platelet-Rich Plasma from the Research to the Clinical Arena: A Journey Toward the Precision Regenerative Medicine. International Journal of Molecular Sciences 2026; 27(2) doi: 10.3390/ijms27021058
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| 34 |
Mehdi Dadashpour, Hamed Mahmoudi, Zahra Rahimi, Raheleh Janghorbanian Poodeh, Hanieh Mousazadeh, Akram Firouzi-Amandi, Yalda Yazdani, Amir Nezami Asl, Abolfazl Akbarzadeh. Sustained in vitro delivery of metformin-loaded mesoporous silica nanoparticles for delayed senescence and stemness preservation of adipose-derived stem cells. Journal of Drug Delivery Science and Technology 2023; 87 doi: 10.1016/j.jddst.2023.104769
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| 35 |
Dinesh Chaudhary, Rabyya Kausar, Jeonghye Lee, Manju Shrestha, Junhyeung Park, Yu Seok Youn, Jong Oh Kim, Jae-Young Lee, Ju-Yeon Kim, Simmyung Yook, Jee-Heon Jeong. Bioengineered hybrid spheroids integrating mesenchymal stem cells and metformin-loaded microspheres for the treatment of sepsis-induced liver injury. Journal of Controlled Release 2026; 393 doi: 10.1016/j.jconrel.2026.114798
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| 36 |
Khanyisani Ziqubu, Sithandiwe E. Mazibuko-Mbeje, Sinenhlanhla X. H. Mthembu, Sihle E. Mabhida, Babalwa U. Jack, Tawanda M. Nyambuya, Bongani B. Nkambule, Albertus K. Basson, Luca Tiano, Phiwayinkosi V. Dludla. Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target. International Journal of Molecular Sciences 2023; 24(3) doi: 10.3390/ijms24032227
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| 37 |
N.L. Cheremshenko, T.V. Symchych, S.V. Gogol, P.A. Virych, V.F. Chekhun. THE COMPLEX EFFECT OF BIFIDOBACTERIUM AND LACTOBACILLUS SPECIES AND METFORMIN ON MACROPHAGES POLARIZATION IN IN VIVO STUDIES. Oncology 2026; 28(2) doi: 10.15407/oncology.2026.02.118
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| 38 |
Li Wang, Zhe Zhang, Eusebio Chiefari. Diabetes Mellitus and Gastric Cancer: Correlation and Potential Mechanisms. Journal of Diabetes Research 2023; 2023 doi: 10.1155/2023/4388437
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| 39 |
Mohammad H. Gharandouq, Mohammad A. Ismail, Tareq Saleh, Malik Zihlif, Nidaa A. Ababneh. Metformin Protects Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons from Oxidative Damage Through Antioxidant Mechanisms. Neurotoxicity Research 2025; 43(2) doi: 10.1007/s12640-025-00734-6
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| 40 |
Fatemeh Sadeghsoltani, Çığır Biray Avci, Parisa Hassanpour, Sanya Haiaty, Mohamad Rahmati, Ali Mota, Reza Rahbarghazi, Maryam Nemati, Mahdi Mahdipour, Mehdi Talebi, Leila Sabour Takanlou, Maryam Sabour Takanlou, Amir Mehdizadeh. Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells. Stem Cell Research & Therapy 2024; 15(1) doi: 10.1186/s13287-024-03813-1
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| 41 |
Daniela Rossin, Maria-Giulia Perrelli, Marco Lo Iacono, Raffaella Rastaldo, Claudia Giachino. Dynamic Interplay Between Autophagy and Oxidative Stress in Stem Cells: Implications for Regenerative Medicine. Antioxidants 2025; 14(6) doi: 10.3390/antiox14060691
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| 42 |
Alec I. McKenzie, Ziad S. Mahmassani, Jonathan J. Petrocelli, Naomi M.M.P. de Hart, Dennis K. Fix, Patrick J. Ferrara, Paul C. LaStayo, Robin L. Marcus, Matthew T. Rondina, Scott A. Summers, Jordan M. Johnson, Joel D. Trinity, Katsuhiko Funai, Micah J. Drummond. Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial. Experimental Gerontology 2022; 163 doi: 10.1016/j.exger.2022.111804
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| 43 |
Somaiah Chinnapaka, Katherine S. Yang, Quinn Flowers, Minhal Faisal, Wayne Vincent Nerone, Joseph Peter Rubin, Asim Ejaz. Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling. Biomedicines 2021; 9(12) doi: 10.3390/biomedicines9121782
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| 44 |
Rania Rashad Omar Omar Taha, Nashwa El-Khazragy, Shereen Hafez Ibrahim, Nermine Hassan. Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells. BMC Oral Health 2026; 26(1) doi: 10.1186/s12903-026-08221-w
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| 45 |
Sanjukta Dasgupta, Moupiya Ghosh, Subhendu Chakrabarty, Gopal Chakrabarti, Amlan Das. Genetic overlap between sarcoidosis and lung cancer: a combined in silico and in vitro approach. Hereditas 2025; 162(1) doi: 10.1186/s41065-025-00503-7
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| 46 |
Jaysukh P. Singh. The Limbal Niche and Its Role in Maintaining Corneal Regeneration. Open Journal of Ophthalmology 2024; 14(01) doi: 10.4236/ojoph.2024.141008
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| 47 |
Humeyra Acikan, Ayse Isik, Emre Sarikaya, Sabahattin Muhtaroglu, Nihal Hatipoglu. The role of short-term metformin in regulating zinc and adipose tissue-derived biomarkers in children with obesity and insulin resistance. BMC Endocrine Disorders 2026; 26(1) doi: 10.1186/s12902-025-02159-w
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| 48 |
Somayeh Ahmadi, Mehdi Dadashpour, Abdolreza Abri, Nosratollah Zarghami. Long-term proliferation and delayed senescence of bone marrow-derived human mesenchymal stem cells on metformin co-embedded HA/Gel electrospun composite nanofibers. Journal of Drug Delivery Science and Technology 2023; 80 doi: 10.1016/j.jddst.2022.104071
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| 49 |
Shiwen Deng, Tong Lei, Hongyu Chen, Huiting Zheng, Zhuangzhuang Xiao, Shanglin Cai, Zhongci Hang, Weini Xiong, Yanqing Yu, Xiaoshuang Zhang, Yanjie Yang, Wangyu Bi, Hongwu Du. Metformin pre-treatment of stem cells from human exfoliated deciduous teeth promotes migration and angiogenesis of human umbilical vein endothelial cells for tissue engineering. Cytotherapy 2022; 24(11) doi: 10.1016/j.jcyt.2022.07.003
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| 50 |
Mahshid Zamani, Nepton Soltani. The role of metformin in extracellular matrix-based three-dimensional cell culture Models: A mini-review on therapeutic potentials. Biochemistry and Biophysics Reports 2026; 45 doi: 10.1016/j.bbrep.2025.102424
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