Effect of alpha 2b interferon on inducement of mIL-2R and treatment of HCV in PBMC from patients with chronic viral hepatitis C

Table 1 The detective results of HCV-RNA in serum and PBMC after treatment with alpha 2b interferon (n, %)

Group	n	HCV-RNA in PBMC		HCV-RNA in serum		Anti-HCV
		Negative	Negative rate	Negative	Negative rate	Negative	Negative rate
Interferon	26	11	42.31a	15	57.69a	17	65.38b
treatment
Routin	22	3	13.64	5	22.73	6	27.27
treatment

^aP < 0.05,

^bP < 0.01 vs interferon treatment.

Table 2 The results of negative rate of HCV-RNA in serum and PBMC

HCV-RNA in serum	HCV-RNA in PBMC		Total	χ2	P
	+	-
+	7	4	11
-	8	7	15	0.75	> 0.05
Total	15	11	26

Table 3 The level of mIL-2R before and after treatment of in-terferon (n, x^-± s, %)

Group	n	mIL-2R (in silence)		mIL-2R (inducement)
		Before treatment	After treatment	Before treatment	After treatment
Interferon treatment	26	2.63 ± 0.70	3.44 ± 0.77bcd	30.34 ± 3.55	33.62 ± 3.95cd
Routin treatment	22	2.43 ± 0.78	2.95 ± 0.72ad	30.07 ± 3.87	30.04 ± 3.73d
Normal control	20	4.54 ± 1.48		37.42 ± 4.10

^aP < 0.05,

^bP < 0.01 vs before and after treatment,

^cP < 0.05,

^dP < 0.01 vs interferon treatment.