Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma

Table 1 Loss of DPC4 expression in pancreatic tissues (%)

Tissues	n	Loss expression of DPC4 (%)
Normal pancreas	8	0 (0)
Non-neoplastic cysts	8	0 (0)
Pancreatic carcinoma	34	8 (23.5)

Table 2 Correlations between loss expression of DPC4 and clinicopathological parameters in pancreatic carcinoma

Parameters	n	Loss expression of DPC4 (%)	P
Age (y)
≥ 60	17	2 (11.8)	0.268
45 ≤ x ＜ 60	11	4 (36.4)
＜ 45	6	2 (33.3)
Sex
Male	22	6 (27.3)	0.681
Female	12	2 (16.7)
Pathological grade
G1+G2	27	4 (14.8)	0.037
G3	7	4 (57.1)
Tumor diameter
≤ 4.5 cm	19	4 (21.2)	1.000
＞ 4.5 cm	15	4 (26.7)
Tumor location
Head	24	6 (25.0)	0.842
Body and tail	10	2 (20.0)
Lymph node
Negative	20	3 (15.0)	0.228
Positive	14	5 (35.7)
TNM staging
I	7	1 (14.3)	0.223
II	11	2 (18.2)
III	11	2 (18.2)
IV	5	3 (60.00)

G1, well differentiated; G2, moderately differentiated; G3, poorly differentiated.

Table 3 Mean and median survivals in pancreatic carcinomas

	Mean survival (days)	Median survival (days)
DPC4 expression	329.94 ± 41.54	319.00 ± 30.32
Loss of DPC4 expression	300.00 ± 61.88	206.00 ± 88.39