Effects of extract F of red-rooted Salvia on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock-reperfusion in rats

doi:10.3748/wjg.v7.i5.672

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Oct 15, 2001 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Original Research

World J Gastroenterol. Oct 15, 2001; 7(5): 672-677
Published online Oct 15, 2001. doi: 10.3748/wjg.v7.i5.672

Table 1 IGML and its IR in gastric corpus and antrum (%, mean ± SD)

	IGML	IR
Group 1 (n = 9)
Corpus	23.18 ± 6.82
Antrum	7.96 ± 0.59^b
Group 2 (n = 7)
Corpus	4.42 ± 1.39^a	82.93
Antrum	1.62 ± 0.37^a	76.64

^bP ＜ 0.01, vs corpus;

^aP ＜ 0.01, vs group 1.

Table 2 DGML and its IR or GR in the gastric corpus and antrum (%, mean ± SD)

	DGML
	0	GR	1	GR	2	IR	3	IR
Group 1 (n = 7)
Corpus	3.01 ± 1.01		8.35 ± 1.95		31.32 ± 4.49		58.44 ± 9.07
Antrum	13.92 ± 2.25^b		26.78 ± 6.06^b		25.98 ± 8.32		34.86 ± 4.96^b
Group 2 (n = 6)
Corpus	22.05 ± 5.96^a	632.56	34.12 ± 8.12^a	308.62	25.96 ± 10.04	17.11	20.32 ± 6.95^a	65.32
Antrum	28.52 ± 8.12^a	104.89	42.42 ± 8.58^a	58.40	14.03 ± 3.13^a	45.98	16.32 ± 4.05^a	53.18

^bP ＜ 0.01, vs corpus;

^aP ＜ 0.01, vs group 1.

Table 3 PGs contents (pg/mg tissue), and their GRs in the gastric corpus and antrum (%, mean ± SD)

Group	PGE₂	GR	6-keto	GR	TXB₂	6-Keto/TXB₂	GR
Group 1 (n = 6)
Corpus	540.48 ± 182.78		714.38 ± 123.74		58.28 ± 6.74	17.38 ± 5.93
Antrum	2218.56 ± 433.12^b		2531.76 ± 492.35^b		62.49 ± 9.51	43.46 ± 8.51^b
Group 2 (n = 6)
Corpus	759.77 ± 192.00^aa	40.75	1248.37 ± 158.54^a	74.75	45.37 ± 7.54^aa	33.42 ± 9.24^a	92.29
Antrum	2465.17 ± 480.36	11.12	2698.31 ± 526.71	56.58	50.02 ± 7.50^a	56.78 ± 5.45^a	30.65

^bP ＜ 0.01, vs corpus;

^aP ＜ 0.01, vs group 1;

^aaP ＜ 0.05, vs group 1.

Table 4 MDA content (nmol/g tissue), SOD activity (U/g tissue), IR of MDA and GR of SOD in the gastric corpus and antrum (%, mean ± SD)

Group	MDA	IR	SOD	GR
Group 1 (n = 6)
Corpus	230.56 ± 19.37		134.29 ± 13.35
Antrum	156.98 ± 16.12^b		187.45 ± 17.67^b
Group 2 (n = 6)
Corpus	94.32 ± 11.32^a	59.09	298.47 ± 20.12^a	122.25
Antrum	90.46 ± 12.45^a	42.37	342.35 ± 26.58^a	82.64

^bP ＜ 0.01, vs corpus;

^aP ＜ 0.01, vs group 1.

Citation: Zhang LH, Yao CB, Li HQ. Effects of extract F of red-rooted Salvia on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock-reperfusion in rats. World J Gastroenterol 2001; 7(5): 672-677
URL: https://www.wjgnet.com/1007-9327/full/v7/i5/672.htm
DOI: https://dx.doi.org/10.3748/wjg.v7.i5.672