FADD and TRADD expression and apoptosis in primary hepatocellular carcinoma

Table 1 Expressions of FADD and TRADD in HCC

Variables	n	FADD		TRADD
		Positive	%	Positive	%
Adjacent tissue	8	5	62.5a	3	37.5
HCC tissue	39	10	25.6	15	38.5
Age (yr)
≤ 60	28	6	21.4	9	32.6
＞ 60	11	4	36.4	6	54.5
Sex
Male	34	9	26.5	13	38.2
Female	5	1	20	2	40
Tumor size (cm)
≥ 5	27	8	29.6	10	37
＜ 5	12	2	16.7	5	41.7
Differentiation
Moderately well	18	5	27.8	4	22.2a
Poorly	21	5	23.8	11	52.4
TNM grade
I/II	21	8	38.1a	9	42.9
IV/IV	18	2	11.1	6	33.3
Metastasis
yes	8	3	37.5	4	50
no	31	7	22.6	11	35.5

^aP ＜ 0.05

Table 2 Correlation between hepatic apoptosis and expressions of FADD and TRADD

Apoptosis	n	FADD expression				TRADD expression
		-	+	++	+++	-	+	++	+++
HCC
+	19	17	1	0	1a	13	3	1	2
++	14	10	0	2	2	9	2	2	1
+++	6	2	1	2	1	2	1	2	1
Non-cancerous adjacent liver tissues
+	6	3	2	1	0	4	2	0	0
++	2	0	1	1	0	1	1	0	0
+++	0	0	0	0	0	0	0	0	0

^aP ＜ 0.05 +/- vs ++/+++