Expression of bcl-2 protein in gastric carcinoma and its significance

Table 1 Correlation between bcl-2 protein expression and clinicopathological parameters of gastric carcinomas

	n	bcl-2 protein expression				Positive rate (%)
		-	+	+ +	+ + +
Age (a)
≤ 59	36	7	4	15	10	80.56
≥ 60	14	2	2	5	5	85.71
Sex
M	34	7	2	13	12	79.41
F	16	2	4	7	3	87.50
Type
Intestinal	28	2	3	13	10	92.86a
Diffuse	22	7	3	7	5	68.18
Grade of differentiation
Well/moderate	18	7	1	5	5	61.11
Poor	22	1	4	12	5	95.45b
Mucoid	10	1	1	3	5	90.00
Tumor size
< 5 cm	31	8	4	11	8	74.19
≥ 5 cm	19	1	2	9	7	94.74
Lymph-node metastasis
Negative	21	4	2	9	6	80.95
Positive	29	5	4	11	9	82.76
Serosal invasion
Absent	25	7	3	9	6	72.00
Present	25	2	3	11	9	92.00
Clinical stages
I and II	32	6	5	12	9	81.25
III and IV	18	3	1	8	6	83.33

^aχ² = 5.082, P < 0.05, vs diffuse-type gastric carcinoma;

^bχ² = 7.298, P < 0.01, vs well/moderately differentiated gastric carcinoma.