Overexpression of P53 and its risk factors in esophageal cancer in urban areas of Xi’an

Table 1 Single variable analysis of risk factors of EC

Factors	Cases	Controls	χ2	OR	95%CI1	P
Smoking
Yes	65	44
No	24	53	15.53	3.26	1.74-6.12	0.0012
Family history of cancer
Yes	43	8
No	46	83	35.46	10.48	4.81-22.48	0.0000

¹CI: confidence interval

Table 2 Logistic regression analysis of risk factors of EC

Factors	OR	Standard error	u value	P
Smoking	3.3	0.2939	4.0760	0.0000
Family history of cancer	3.0	0.2922	3.7090	0.0002

Table 3 Correlation between clinical features and overexpression of p53 in EC

Clinical features	P53 status		Univariate		Multivariate
	Overexpression	Normal	χ2	P	OR	P
Age	55.41 ± 8.831	55.32 ± 11.071	1.5836	0.9710	1.0104	0.8447
Sex
Male	20	22
Female	14	9	1.1497	0.5628	1.3611	0.7820
Smoking
Yes	30	20
No	4	11	3.8898	0.0486	3.1200	0.0041
Family history of cancer
Yes	24	7
No	10	24	17.2834	0.0001	15.8100	0.0002

¹mean ± SD.