Characteristics of gut microbiota and metabolites in patients with ulcerative colitis with fatigue

Table 1 Comparison of baseline data of enrolled subjects

Item	HUCF group (n = 30)	HUCN group (n = 30)	HHF group (n = 30)	HHN group (n = 30)	P value
Age (year)	45.10 ± 12.48	47.43 ± 13.70	44.00 ± 15.10	48.77 ± 13.67	0.533
Gender (M/F)	15/15	12/18	22/8	14/16	0.055
BMI (kg/m2)	21.81 ± 1.21	22.56 ± 0.67	22.27 ± 0.80	23.60 ± 0.78	0.753
FS-14 score	8.89 ± 0.37	2.07 ± 0.47	7.33 ± 0.39	2.00 ± 0.58	0.000
TCM fatigue score	39.40 ± 2.85	12.88 ± 2.14	31.43 ± 2.86	10.00 ± 4.52	0.000
Disease phase			-	-	0.072
Active phase	25 (56.82)	19 (43.18)	-	-
Remission phase	5 (31.25)	11 (68.75)	-	-
Disease extent			-	-	0.534
Proctitis	9 (40.91)	13 (59.09)	-	-
Left-sided colitis	10 (52.63)	9 (47.37)	-	-
Extensive colitis	11 (57.90))	8 (42.10)	-	-
Mayo score			-	-	0.065
0	5 (31.25)	11 (68.75)	-	-
1	5 (45.45)	6 (54.55)	-	-
2	12 (50.00)	12 (50.50)	-	-
3	8 (88.89)	1 (11.11)	-	-

Data were showed as mean ± SD or n (%). HHF: Healthy with fatigue; HHN: Healthy without fatigue; HUCF: Ulcerative colitis with fatigue; HUCN: Ulcerative colitis without fatigue; M: Male; F: Female; BMI: Body mass index; FS-14: Fatigue Scale-14; TCM: Traditional Chinese medicine.