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©The Author(s) 2026.
World J Gastroenterol. Jan 14, 2026; 32(2): 112395
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.112395
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.112395
Table 1 Multivariable logistic regression analysis evaluating the association between having gastroesophageal reflux symptoms and sociodemographic, lifestyle, and clinical characteristics, n (%)
| Participants with GERS | Participants without GERS (n = 1584, 49.3%)1 | Participants with GERS vs participants without GERS, OR (95%CI) | |
| Age, years2 | |||
| 18-34 | 224 (14.8) | 300 (19.8) | Reference category |
| 35-54 | 461 (30.4) | 447 (29.5) | 0.896 (0.425-1.889) |
| 55-75 | 832 (54.8) | 768 (50.7) | 0.534 (0.256-1.114) |
| Gender2 | |||
| Female or non-binary | 783 (51.6) | 726 (47.9) | Reference category |
| Male | 734 (48.4) | 789 (52.1) | 0.720 (0.509-1.019) |
| Educational level3 | |||
| Lower | 292 (19.3) | 243 (16.1) | Reference category |
| Middle | 535 (35.3) | 525 (34.7) | 0.964 (0.607-1.531) |
| Higher | 689 (45.4) | 746 (49.3) | 0.888 (0.565-1.396) |
| Civil status3 | |||
| Living without a partner | 343 (22.6) | 417 (27.5) | Reference category |
| Living with a partner | 1173 (77.4) | 1097 (72.5) | 1.292 (0.864-1.933) |
| Migration background3 | |||
| Dutch background | 1417 (93.5) | 1439 (95.0) | |
| Western or non-Western background | 99 (6.5) | 75 (5.0) | |
| Waist circumference (cm)4,5 | |||
| Normal waist circumference | 456 (56.4) | 569 (70.8) | Reference category |
| Increased waist circumference | 353 (43.6) | 235 (29.2) | 1.513 (1.068-2.141) |
| Smoking behavior (pack-years), median (IQR)6 | 9.0 (17.00) | 7.5 (13.50) | 1.011 (0.998-1.023) |
| Alcohol consumption (units per week)7 | |||
| < 7 | 957 (73.3) | 980 (75.0) | |
| ≥ 7 | 349 (26.7) | 326 (25.0) | |
| Hypertension8 | |||
| No | 1185 (78.7) | 1273 (84.6) | Reference category |
| Yes | 321 (21.3) | 232 (15.4) | 1.174 (0.753-1.832) |
| Diabetes9 | |||
| No | 1405 (93.3) | 1446 (96.2) | Reference category |
| Yes | 101 (6.7) | 57 (3.8) | 0.853 (0.431-1.689) |
| Hypercholesterolemia10 | |||
| No | 1208 (80.3) | 1309 (87.1) | Reference category |
| Yes | 297 (19.7) | 194 (12.9) | 1.694 (1.051-2.731) |
| Family history of esophageal cancer11 | |||
| No or unknown | 940 (82.1) | 1047 (87.3) | Reference category |
| Yes | 205 (17.9) | 152 (12.7) | 0.870 (0.552-1.372) |
Table 2 Multivariable logistic regression analysis evaluating the association between consulting a primary care provider for gastroesophageal reflux symptoms and sociodemographic, lifestyle, and clinical characteristics, n (%)
| Participants with GERS who had ever consulted a PCP (n = 661, 42.0%)1 | Participants with GERS who had never consulted a PCP (n = 904, 57.5%)1 | Participants with GERS who had ever consulted a PCP vs who had never consulted a PCP, OR (95%CI) | |
| Age, years2 | |||
| 18-34 | 54 (8.5) | 170 (19.3) | Reference category |
| 35-54 | 173 (27.2) | 288 (32.7) | 1.532 (1.053-2.230) |
| 55-75 | 410 (64.4) | 422 (48.0) | 2.244 (1.578-3.192) |
| Gender2 | |||
| Female or non-binary | 335 (52.6) | 448 (50.9) | |
| Male | 302 (47.4) | 432 (49.1) | |
| Educational level3 | |||
| Lower | 154 (24.2) | 138 (15.7) | Reference category |
| Middle | 234 (36.7) | 301 (34.2) | 0.715 (0.527-0.971) |
| Higher | 249 (39.1) | 440 (50.1) | 0.582 (0.432-0.784) |
| Civil status3 | |||
| Living without a partner | 139 (21.8) | 204 (23.2) | |
| Living with a partner | 498 (78.2) | 675 (76.8) | |
| Migration background3 | |||
| Dutch background | 594 (93.2) | 823 (93.6) | |
| Western or non-Western background | 43 (6.8) | 56 (6.4) | |
| Family history of esophageal cancer4 | |||
| No or unknown | 360 (79.6) | 580 (83.7) | |
| Yes | 92 (20.4) | 113 (16.3) | |
| Duration of GERS1, years | |||
| < 1 | 142 (21.5) | 415 (45.9) | Reference category |
| 1-5 | 169 (25.6) | 242 (26.8) | 2.099 (1.578-2.791) |
| 5-10 | 103 (15.6) | 109 (12.1) | 2.655 (1.890-3.730) |
| > 10 | 247 (37.4) | 138 (15.3) | 4.827 (3.602-6.469) |
| Age at onset GERS1, years | |||
| < 30 | 243 (36.8) | 367 (40.6) | |
| 30-50 | 262 (39.6) | 308 (34.1) | |
| > 50 | 156 (23.6) | 229 (25.3) |
- Citation: Huibertse LJ, Sijben J, Peters Y, Siersema PD. Self-management and help-seeking behavior for gastroesophageal reflux symptoms: A population-based survey. World J Gastroenterol 2026; 32(2): 112395
- URL: https://www.wjgnet.com/1007-9327/full/v32/i2/112395.htm
- DOI: https://dx.doi.org/10.3748/wjg.v32.i2.112395
