Cystic tumors of the pancreas: Current perspectives on diagnosis and management

Table 1 Comparative overview of major international guidelines for the management of pancreatic cystic lesions

	Fukuoka (2017)	AGA (2015)	European (2018)
Focus	IPMN and MCN	All PCLs	All PCLs
High-risk stigmata	Yes	Not emphasized	Yes
Role of EUS-FNA	Essential for worrisome	Only if ≥ 2 risk factors	Strongly recommended
Surveillance duration	Lifelong	Stop after 5 years stable	Tailored, often lifelong
Role of MDT	Optional	Not emphasized	Strongly recommended
Molecular testing	Not addressed	Not included	Recommended in selected cases

AGA: American Gastroenterological Association; EUS: Endoscopic ultrasound; FNA: Fine-needle aspiration; MDT: Multidisciplinary team; IPMN: Intraductal papillary mucinous neoplasm; MCN: Mucinous cystic neoplasm; PCLs: Pancreatic cystic lesions.